Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 1972083..1972673 Replicon chromosome
Accession NZ_LS483499
Organism Tatumella ptyseos strain NCTC11468

Toxin (Protein)


Gene name pemK Uniprot ID A0A085JF07
Locus tag DQM83_RS09685 Protein ID WP_029991547.1
Coordinates 1972083..1972415 (-) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID A0A085JF06
Locus tag DQM83_RS09690 Protein ID WP_029991546.1
Coordinates 1972416..1972673 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQM83_RS09655 1967396..1967770 + 375 WP_029991550.1 VOC family protein -
DQM83_RS09665 1968373..1969635 + 1263 WP_029991549.1 integrase arm-type DNA-binding domain-containing protein -
DQM83_RS09670 1970387..1971274 - 888 WP_029991548.1 integrase domain-containing protein -
DQM83_RS09685 1972083..1972415 - 333 WP_029991547.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
DQM83_RS09690 1972416..1972673 - 258 WP_029991546.1 antitoxin Antitoxin
DQM83_RS09695 1973021..1973163 - 143 Protein_1835 helix-turn-helix domain-containing protein -
DQM83_RS09700 1973224..1973685 - 462 WP_029991545.1 hypothetical protein -
DQM83_RS09705 1974049..1976004 + 1956 WP_029991543.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-108)

Antitoxin

Antitoxin PemI-like

(4-84)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11703.51 Da        Isoelectric Point: 9.3429

>T292670 WP_029991547.1 NZ_LS483499:c1972415-1972083 [Tatumella ptyseos]
MDRGEIWLVSLDPVAGHEQSGKRPVLIVSPASFNKLTRLPVVVPVTSGGNFARAAGFAVSLDGAGTKTAGIIRCDQPRTI
DMAARNGKRLEQIPDSIVNEVLARLEAILN

Download         Length: 333 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9356.83 Da        Isoelectric Point: 4.4354

>AT292670 WP_029991546.1 NZ_LS483499:c1972673-1972416 [Tatumella ptyseos]
MYTTRLKKVGGSVMLAVPPAVLKTLALSTDSEVGMTIDNGCLIIEPQKRPRYSLDELLAQCDPHAEMSEEDREWIDAPAV
GKEIL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A085JF07

Antitoxin

Source ID Structure
AlphaFold DB A0A085JF06

References