Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 416813..417531 Replicon chromosome
Accession NZ_LS483498
Organism Morganella morganii strain NCTC12028

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag DQM84_RS02030 Protein ID WP_111759529.1
Coordinates 417211..417531 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag DQM84_RS02025 Protein ID WP_111759528.1
Coordinates 416813..417169 (+) Length 119 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQM84_RS01990 413168..413602 + 435 WP_111759521.1 hypothetical protein -
DQM84_RS01995 413622..414425 + 804 WP_111759522.1 hypothetical protein -
DQM84_RS02005 414642..415076 + 435 WP_111759524.1 hypothetical protein -
DQM84_RS02010 415190..416011 + 822 WP_111759525.1 DUF945 domain-containing protein -
DQM84_RS02015 416081..416551 + 471 WP_111759526.1 DNA repair protein RadC -
DQM84_RS02020 416560..416781 + 222 WP_111759527.1 DUF987 family protein -
DQM84_RS02025 416813..417169 + 357 WP_111759528.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
DQM84_RS02030 417211..417531 + 321 WP_111759529.1 TA system toxin CbtA family protein Toxin
DQM84_RS02035 417645..418481 + 837 WP_111759530.1 DUF4942 domain-containing protein -
DQM84_RS02040 418873..420147 + 1275 WP_004234643.1 integrase arm-type DNA-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 390864..433818 42954


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(12-105)

Antitoxin

Antitoxin CbeA

(18-117)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12096.84 Da        Isoelectric Point: 6.0590

>T292666 WP_111759529.1 NZ_LS483498:417211-417531 [Morganella morganii]
MHISTVPVTVPVSSRLSPVQVWQQLLTYLLEHYYGLTLNDTPFHDDSAIQEHIEAGITLADAVNFLVERYELIRTDRKGF
TWQGQTPFLTAIDILRARRATGLMNI

Download         Length: 321 bp

Antitoxin


Download         Length: 119 a.a.        Molecular weight: 13018.60 Da        Isoelectric Point: 6.0607

>AT292666 WP_111759528.1 NZ_LS483498:416813-417169 [Morganella morganii]
MQSTTLSGTSAENATCLQWGLKRNITPCFGARLVQEGNRLYFLADRAGFNGSFSDDEALRLDQAFPLIMKQLERMLTTGE
LDPRSQHSVALHHNGLTSEADTLGSHGYVYIAIYPSQP

Download         Length: 357 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References