Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 957674..958340 Replicon chromosome
Accession NZ_LS483492
Organism Serratia rubidaea strain NCTC10848

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag DQN11_RS04510 Protein ID WP_105232394.1
Coordinates 957921..958340 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag DQN11_RS04505 Protein ID WP_105232395.1
Coordinates 957674..957940 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQN11_RS04480 952830..953483 + 654 WP_105232400.1 hypothetical protein -
DQN11_RS04485 953480..954799 + 1320 WP_105232399.1 MHS family MFS transporter -
DQN11_RS04490 954831..955439 - 609 WP_105232398.1 HD domain-containing protein -
DQN11_RS04495 955634..956314 + 681 WP_105232397.1 hemolysin III family protein -
DQN11_RS04500 956351..957343 - 993 WP_105232396.1 tRNA-modifying protein YgfZ -
DQN11_RS04505 957674..957940 + 267 WP_105232395.1 FAD assembly factor SdhE Antitoxin
DQN11_RS04510 957921..958340 + 420 WP_105232394.1 hypothetical protein Toxin
DQN11_RS04515 958371..958889 - 519 WP_105232393.1 flavodoxin FldB -
DQN11_RS04520 958981..959880 + 900 WP_105232392.1 site-specific tyrosine recombinase XerD -
DQN11_RS04525 959908..960624 + 717 WP_015673664.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
DQN11_RS04530 960637..962367 + 1731 WP_105232391.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16481.54 Da        Isoelectric Point: 11.5037

>T292655 WP_105232394.1 NZ_LS483492:957921-958340 [Serratia rubidaea]
VAQWRCDVRISWRTQLISLLAHGALILLILISPWPESYDPVWLLLLTLVVFECIRSQTRIASRQGELRLLSAPQRVIWQG
KEWRLVRRPWMLRYGMLLTLQASGKRKRRRLWLASDCISSAEWRQLCQRMRLVKDESEG

Download         Length: 420 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10405.90 Da        Isoelectric Point: 5.0964

>AT292655 WP_105232395.1 NZ_LS483492:957674-957940 [Serratia rubidaea]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSEEDKALFVRLLQCDDPDLFNWLMNHGAPQDAELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References