29264

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 5245825..5246492 Replicon chromosome
Accession NC_020815
Organism Xanthomonas citri subsp. citri Aw12879

Toxin (Protein)


Gene name vapC Uniprot ID M4U0C6
Locus tag XCAW_RS22555 Protein ID WP_005916679.1
Coordinates 5246076..5246492 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID M4U000
Locus tag XCAW_RS22550 Protein ID WP_005916676.1
Coordinates 5245825..5246079 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XCAW_RS22525 5241947..5242166 + 220 Protein_4421 RNA 2'-phosphotransferase -
XCAW_RS22530 5242323..5243588 + 1266 WP_015463799.1 cardiolipin synthase B -
XCAW_RS22535 5243614..5244141 - 528 WP_005916668.1 hypothetical protein -
XCAW_RS22540 5244380..5244586 + 207 WP_003489327.1 hypothetical protein -
XCAW_RS22545 5244573..5245679 + 1107 WP_005916674.1 type II toxin-antitoxin system RelE/ParE family toxin -
XCAW_RS22550 5245825..5246079 + 255 WP_005916676.1 Arc family DNA-binding protein Antitoxin
XCAW_RS22555 5246076..5246492 + 417 WP_005916679.1 type II toxin-antitoxin system VapC family toxin Toxin
XCAW_RS26220 5246614..5246886 - 273 WP_125459513.1 hypothetical protein -
XCAW_RS26225 5246945..5247157 - 213 WP_015472901.1 hypothetical protein -
XCAW_RS22560 5247414..5249033 + 1620 WP_015463800.1 hypothetical protein -
XCAW_RS22565 5249137..5249535 - 399 WP_004429277.1 DUF2384 domain-containing protein -
XCAW_RS22570 5249851..5250282 + 432 WP_005922907.1 hypothetical protein -
XCAW_RS25460 5250311..5250637 - 327 Protein_4433 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-127)

Antitoxin

Arc-like DNA binding domain

(1-39)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14795.09 Da        Isoelectric Point: 5.6920

>T29264 WP_005916679.1 NC_020815:5246076-5246492 [Xanthomonas citri subsp. citri Aw12879]
VILLDTNVISELWRPQPNPQVVAWIDAQAVETLFLSVVTVAELRFGIAVMPKGRKRSTLHARLEGEVLPLFDGRLLAFDL
DASHAFAALASKARTAGLTLGRADAYIAATAAAQGLTVATRDTAPFEAMALDVINPWS

Download         Length: 417 bp

>T29264 NC_020815:5246076-5246492 [Xanthomonas citri subsp. citri Aw12879]
GTGATCCTGCTCGATACCAATGTCATCTCCGAACTTTGGCGGCCTCAGCCTAATCCGCAGGTCGTCGCCTGGATCGATGC
ACAAGCTGTCGAGACACTGTTCCTGTCGGTCGTGACGGTGGCTGAACTCCGTTTCGGTATTGCCGTGATGCCCAAGGGCC
GAAAGCGATCCACCTTGCATGCTCGGTTGGAGGGCGAGGTATTGCCACTGTTCGACGGGCGCCTGCTCGCATTCGATCTG
GATGCATCACACGCATTTGCGGCGCTTGCATCGAAAGCCAGAACCGCAGGACTCACACTCGGGCGCGCCGATGCCTACAT
CGCTGCAACAGCAGCCGCGCAAGGATTGACCGTTGCCACTCGCGACACGGCACCATTCGAGGCGATGGCGTTAGACGTCA
TTAACCCTTGGAGTTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 8996.53 Da        Isoelectric Point: 11.3362

>AT29264 WP_005916676.1 NC_020815:5245825-5246079 [Xanthomonas citri subsp. citri Aw12879]
MPSFTVRNIPDDVHRAIRARAALHGRSTEAEIRAILELAAKPADRVKLGSLLVSIGRDAGLTAKEANAFDKLRGKAAIKP
IGLK

Download         Length: 255 bp

>AT29264 NC_020815:5245825-5246079 [Xanthomonas citri subsp. citri Aw12879]
ATGCCTTCTTTCACCGTCCGCAATATCCCAGACGACGTGCATCGCGCGATCCGCGCGCGGGCTGCACTTCATGGCCGCAG
CACCGAAGCGGAGATCCGCGCAATCCTTGAATTGGCGGCCAAACCCGCAGACCGGGTCAAACTCGGCTCACTGCTGGTGA
GCATCGGCCGCGACGCCGGCCTGACCGCAAAAGAGGCCAATGCCTTCGACAAGCTGCGCGGCAAGGCGGCGATCAAGCCG
ATCGGTCTGAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB M4U0C6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YKJ0

References