Detailed information of TA system TA029263

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN-MazE
• Location: 2701864..2702497
• Replicon: chromosome
• Accession: NC_020815
• Organism: Xanthomonas citri subsp. citri Aw12879

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: XCAW_RS11670
• Protein ID: WP_015463212.1
• Coordinates: 2701864..2702277 (-)
• Length: 138 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: M4TWF0
• Locus tag: XCAW_RS11675
• Protein ID: WP_015463213.1
• Coordinates: 2702264..2702497 (-)
• Length: 78 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XCAW_RS11660	2697556..2699736	+	2181	WP_011051394.1	TonB-dependent siderophore receptor	-
XCAW_RS11665	2699945..2701459	+	1515	WP_015463210.1	conjugal transfer protein TraG N-terminal domain-containing protein	-
XCAW_RS24480	2701475..2701837	-	363	WP_015463211.1	DUF3742 family protein	-
XCAW_RS11670	2701864..2702277	-	414	WP_015463212.1	PIN domain-containing protein	Toxin
XCAW_RS11675	2702264..2702497	-	234	WP_015463213.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
XCAW_RS11680	2702779..2703786	+	1008	WP_199822817.1	DUF4917 family protein	-
XCAW_RS11685	2703919..2704317	-	399	WP_099521978.1	hypothetical protein	-
XCAW_RS11690	2704769..2705344	+	576	WP_011051400.1	sigma-70 family RNA polymerase sigma factor	-
XCAW_RS11695	2705325..2706374	+	1050	WP_015472205.1	FecR domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (8-119)

Antitoxin

• SpoVT-AbrB domain (5-45)

Sequences

Toxin

Protein

• Length: 138 a.a.
• Molecular weight: 15221.65 Da
• Isoelectric Point: 6.3225

>T29263 WP_015463212.1 NC_020815:c2702277-2701864 [Xanthomonas citri subsp. citri Aw12879]
MAAGKGKVFLDSNVVLYLLSEDAVKADGAEALLQRRPVISVQVLNEVTHVCVRKLKMGWDEVGQFLALVRSFCKIVPLTV
DVHDRARQLAERHQLSFYDACIVAAAAIEGCQTLYSEDMHHGLIIEESLSIRNPFNV

Nucleotide

• Length: 414 bp

>T29263 NC_020815:c2702277-2701864 [Xanthomonas citri subsp. citri Aw12879]
ATGGCCGCGGGTAAGGGCAAAGTGTTTCTCGACAGCAACGTGGTGCTCTACCTGCTGTCGGAGGATGCGGTGAAGGCGGA
CGGCGCGGAGGCATTGCTGCAGCGCAGGCCCGTCATCAGTGTGCAGGTGCTCAATGAAGTGACCCACGTCTGCGTTCGCA
AGCTCAAGATGGGCTGGGACGAAGTCGGGCAGTTCCTTGCGTTGGTGCGATCGTTCTGCAAGATAGTGCCTCTGACGGTC
GATGTTCACGACCGTGCGCGCCAGCTGGCGGAGCGGCACCAATTGTCGTTCTACGACGCGTGCATCGTGGCGGCGGCCGC
CATCGAAGGGTGCCAGACCCTCTACTCCGAAGACATGCACCACGGCCTCATCATCGAAGAGAGCCTGTCGATTCGGAACC
CGTTCAACGTCTGA

Antitoxin

Protein

• Length: 78 a.a.
• Molecular weight: 8663.97 Da
• Isoelectric Point: 8.7848

>AT29263 WP_015463213.1 NC_020815:c2702497-2702264 [Xanthomonas citri subsp. citri Aw12879]
MQVAKWGNSLAVRLPSSLVEALELREGDDIEIVVDDPRLFAVRKKPGPEAMLERLRAFRGKLPADFKFNRDEANGRG

Nucleotide

• Length: 234 bp

>AT29263 NC_020815:c2702497-2702264 [Xanthomonas citri subsp. citri Aw12879]
ATGCAAGTCGCGAAGTGGGGTAACAGCCTGGCGGTGCGCCTGCCGTCCAGTCTGGTGGAAGCGCTGGAACTGCGCGAGGG
CGACGACATCGAGATCGTCGTCGATGATCCGCGATTGTTCGCGGTGCGCAAGAAGCCGGGTCCGGAGGCCATGTTGGAGC
GGCTGCGTGCCTTCCGGGGCAAGTTGCCCGCAGATTTCAAGTTCAACCGGGACGAGGCCAATGGCCGCGGGTAA

Structures

Antitoxin

• AlphaFold DB: M4TWF0