Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 1122160..1122969 Replicon chromosome
Accession NZ_LS483482
Organism Staphylococcus lugdunensis strain NCTC12217

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag DQL46_RS05365 Protein ID WP_002458758.1
Coordinates 1122799..1122969 (+) Length 57 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag DQL46_RS05360 Protein ID WP_070648686.1
Coordinates 1122160..1122759 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL46_RS05340 1117748..1119205 + 1458 WP_002477974.1 ABC transporter substrate-binding protein/permease -
DQL46_RS05345 1119198..1119922 + 725 Protein_1012 amino acid ABC transporter ATP-binding protein -
DQL46_RS05350 1120380..1121522 + 1143 WP_103284502.1 tRNA epoxyqueuosine(34) reductase QueG -
DQL46_RS05355 1121524..1121994 + 471 WP_002458756.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
DQL46_RS05360 1122160..1122759 + 600 WP_070648686.1 glucosamine-6-phosphate isomerase Antitoxin
DQL46_RS05365 1122799..1122969 + 171 WP_002458758.1 hypothetical protein Toxin
DQL46_RS05370 1123143..1123538 + 396 WP_002458759.1 hypothetical protein -
DQL46_RS05375 1123666..1125051 + 1386 WP_070648688.1 class II fumarate hydratase -
DQL46_RS05380 1125116..1125952 - 837 WP_002477978.1 RluA family pseudouridine synthase -
DQL46_RS05385 1126120..1127232 + 1113 WP_060795476.1 GAF domain-containing sensor histidine kinase -
DQL46_RS05390 1127254..1127877 + 624 WP_002477980.1 response regulator transcription factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(131-195)


Sequences

Toxin        


Download         Length: 57 a.a.        Molecular weight: 6565.10 Da        Isoelectric Point: 4.6723

>T292623 WP_002458758.1 NZ_LS483482:1122799-1122969 [Staphylococcus lugdunensis]
MSKEKKSRLNYHEEENAMVENLEDLKELGKEMEHISEKNDEEKVNQSHDTSKSSNS

Download         Length: 171 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22637.55 Da        Isoelectric Point: 4.9539

>AT292623 WP_070648686.1 NZ_LS483482:1122160-1122759 [Staphylococcus lugdunensis]
MAMNFKVFENKDQVAEYSADIIRKQFNNNPTTIAGFHLNKEASPVLDMLKKNVDQHAVDFSQINILDYDQNQEYFKALGV
PESQIYPISYDQDAEAFISDKIKTKDNKGKLMLQVASIDDQGNLNISLRQGLLNAREIILVITGHNKKEVVEKLYNENGK
SNFEPADLKAHRMVTVILDEAAAEGLPEDVRHYFTDRFA

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References