Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 1394109..1394699 Replicon chromosome
Accession NZ_LS483470
Organism Leminorella richardii strain NCTC12151

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag DQM29_RS06580 Protein ID WP_111739950.1
Coordinates 1394367..1394699 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag DQM29_RS06575 Protein ID WP_111739949.1
Coordinates 1394109..1394366 (+) Length 86 a.a.

Genomic Context

DQM29_RS06550DQM29_RS06555DQM29_RS06560DQM29_RS06565DQM29_RS06570DQM29_RS06575DQM29_RS06580DQM29_RS06585DQM29_RS06590DQM29_RS06595
Location: 1390250..1390681 (432 bp)
Type: Others
Protein ID: WP_111739944.1
Location: 1390776..1391447 (672 bp)
Type: Others
Protein ID: WP_111739945.1
Location: 1391533..1392696 (1164 bp)
Type: Others
Protein ID: WP_111739946.1
Location: 1392979..1393332 (354 bp)
Type: Others
Protein ID: WP_111739947.1
Location: 1393337..1393639 (303 bp)
Type: Others
Protein ID: WP_111739948.1
Location: 1394109..1394366 (258 bp)
Type: Antitoxin
Protein ID: WP_111739949.1
Location: 1394367..1394699 (333 bp)
Type: Toxin
Protein ID: WP_111739950.1
Location: 1395208..1396419 (1212 bp)
Type: Others
Protein ID: WP_111739951.1
Location: 1396436..1398118 (1683 bp)
Type: Others
Protein ID: WP_111739952.1
Location: 1398335..1399207 (873 bp)
Type: Others
Protein ID: WP_111739953.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
DQM29_RS065501390250..1390681+432WP_111739944.1carboxymuconolactone decarboxylase family protein-
DQM29_RS065551390776..1391447+672WP_111739945.1MmcQ/YjbR family DNA-binding protein-
DQM29_RS065601391533..1392696+1164WP_111739946.1winged helix-turn-helix domain-containing protein-
DQM29_RS065651392979..1393332+354WP_111739947.1type II toxin-antitoxin system RelE/ParE family toxin-
DQM29_RS065701393337..1393639+303WP_111739948.1XRE family transcriptional regulator-
DQM29_RS065751394109..1394366+258WP_111739949.1antitoxinAntitoxin
DQM29_RS065801394367..1394699+333WP_111739950.1type II toxin-antitoxin system PemK/MazF family toxinToxin
DQM29_RS065851395208..1396419+1212WP_111739951.1hypothetical protein-
DQM29_RS065901396436..1398118+1683WP_111739952.1ATP-binding protein-
DQM29_RS065951398335..1399207-873WP_111739953.1integrase domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-108)

Antitoxin

Antitoxin PemI-like

(4-84)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11785.55 Da        Isoelectric Point: 10.7301

>T292604 WP_111739950.1 NZ_LS483470:1394367-1394699 [Leminorella richardii]
MDRGEIWLVSLDPIAGHEQSGKRPVLIVSKASFNNLTRLPVVVPVTSGGNFARTAGFTVSLDGSGTKTTGVIRCDQPRTI
DIGARNGKRLERIPDSITNEVLARLGAILF

Download         Length: 333 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9428.93 Da        Isoelectric Point: 4.4620

>AT292604 WP_111739949.1 NZ_LS483470:1394109-1394366 [Leminorella richardii]
MYTTRLKKVGGSIMLTVPPAVLKTLALSTDSEVGMTIENGCLIIEPQKRPRYSLEELLAQCDPHAEMSEEDREWIDAPAV
GKEIL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References