Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 1394109..1394699 Replicon chromosome
Accession NZ_LS483470
Organism Leminorella richardii strain NCTC12151

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag DQM29_RS06580 Protein ID WP_111739950.1
Coordinates 1394367..1394699 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag DQM29_RS06575 Protein ID WP_111739949.1
Coordinates 1394109..1394366 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQM29_RS06550 1390250..1390681 + 432 WP_111739944.1 carboxymuconolactone decarboxylase family protein -
DQM29_RS06555 1390776..1391447 + 672 WP_111739945.1 MmcQ/YjbR family DNA-binding protein -
DQM29_RS06560 1391533..1392696 + 1164 WP_111739946.1 winged helix-turn-helix domain-containing protein -
DQM29_RS06565 1392979..1393332 + 354 WP_111739947.1 type II toxin-antitoxin system RelE/ParE family toxin -
DQM29_RS06570 1393337..1393639 + 303 WP_111739948.1 XRE family transcriptional regulator -
DQM29_RS06575 1394109..1394366 + 258 WP_111739949.1 antitoxin Antitoxin
DQM29_RS06580 1394367..1394699 + 333 WP_111739950.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
DQM29_RS06585 1395208..1396419 + 1212 WP_111739951.1 hypothetical protein -
DQM29_RS06590 1396436..1398118 + 1683 WP_111739952.1 ATP-binding protein -
DQM29_RS06595 1398335..1399207 - 873 WP_111739953.1 integrase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-108)

Antitoxin

Antitoxin PemI-like

(4-84)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11785.55 Da        Isoelectric Point: 10.7301

>T292604 WP_111739950.1 NZ_LS483470:1394367-1394699 [Leminorella richardii]
MDRGEIWLVSLDPIAGHEQSGKRPVLIVSKASFNNLTRLPVVVPVTSGGNFARTAGFTVSLDGSGTKTTGVIRCDQPRTI
DIGARNGKRLERIPDSITNEVLARLGAILF

Download         Length: 333 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9428.93 Da        Isoelectric Point: 4.4620

>AT292604 WP_111739949.1 NZ_LS483470:1394109-1394366 [Leminorella richardii]
MYTTRLKKVGGSIMLTVPPAVLKTLALSTDSEVGMTIENGCLIIEPQKRPRYSLEELLAQCDPHAEMSEEDREWIDAPAV
GKEIL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References