Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1042050..1042585 Replicon chromosome
Accession NZ_LS483470
Organism Leminorella richardii strain NCTC12151

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DQM29_RS04925 Protein ID WP_111739580.1
Coordinates 1042298..1042585 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DQM29_RS04920 Protein ID WP_111739579.1
Coordinates 1042050..1042301 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQM29_RS04895 1037225..1038247 + 1023 WP_170126490.1 thiosulfate ABC transporter substrate-binding protein CysP -
DQM29_RS04900 1038250..1039083 + 834 WP_111741998.1 sulfate/thiosulfate ABC transporter permease CysT -
DQM29_RS04905 1039083..1039958 + 876 WP_111739576.1 sulfate/thiosulfate ABC transporter permease CysW -
DQM29_RS04910 1039948..1041042 + 1095 WP_111739577.1 sulfate/thiosulfate ABC transporter ATP-binding protein CysA -
DQM29_RS04915 1041071..1041958 + 888 WP_111739578.1 cysteine synthase CysM -
DQM29_RS04920 1042050..1042301 + 252 WP_111739579.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
DQM29_RS04925 1042298..1042585 + 288 WP_111739580.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DQM29_RS04930 1042714..1044678 - 1965 WP_111739581.1 MacB family efflux pump subunit -
DQM29_RS04935 1044683..1045873 - 1191 WP_111739582.1 efflux RND transporter periplasmic adaptor subunit -
DQM29_RS04940 1046089..1046765 + 677 Protein_966 response regulator transcription factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11055.07 Da        Isoelectric Point: 10.4228

>T292601 WP_111739580.1 NZ_LS483470:1042298-1042585 [Leminorella richardii]
MSYAVKFRRDALKEWQKLDKAIQQQFAKKLKKCCEEPHLPAARLSGMPDCYKIKLRSSGFRLVYQVINDELLVVVVAVGK
RERSGVYHLASERMR

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9170.52 Da        Isoelectric Point: 4.1947

>AT292601 WP_111739579.1 NZ_LS483470:1042050-1042301 [Leminorella richardii]
MPNLILSDISASVSELKKNPMATVNAGAGYPVAILNRNQPAFYCVPAELYEQILDALDEHELVKLVKERQGQPLVEVDLD
SYL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References