29260

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 363909..364270 Replicon chromosome
Accession NC_020815
Organism Xanthomonas citri subsp. citri Aw12879

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XCAW_RS01450 Protein ID WP_005914328.1
Coordinates 364136..364270 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag XCAW_RS01445 Protein ID WP_003486606.1
Coordinates 363909..364061 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XCAW_RS01415 359009..359692 - 684 WP_011052674.1 dTMP kinase -
XCAW_RS01420 360130..360672 - 543 WP_003486615.1 GTPase -
XCAW_RS01425 360669..361586 - 918 WP_011052673.1 hypothetical protein -
XCAW_RS01430 361683..362042 - 360 WP_003486613.1 hypothetical protein -
XCAW_RS01435 362106..362558 - 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
XCAW_RS01440 362879..363802 + 924 WP_005927745.1 arginase -
XCAW_RS01445 363909..364061 + 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
XCAW_RS01450 364136..364270 + 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XCAW_RS01455 364497..364706 + 210 WP_003486601.1 CsbD family protein -
XCAW_RS01460 364887..366176 + 1290 WP_015463705.1 tryptophan--tRNA ligase -
XCAW_RS01465 366215..367249 + 1035 WP_011052671.1 MBL fold metallo-hydrolase -
XCAW_RS01470 367441..369132 + 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T29260 WP_005914328.1 NC_020815:364136-364270 [Xanthomonas citri subsp. citri Aw12879]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T29260 NC_020815:364136-364270 [Xanthomonas citri subsp. citri Aw12879]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT29260 WP_003486606.1 NC_020815:363909-364061 [Xanthomonas citri subsp. citri Aw12879]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT29260 NC_020815:363909-364061 [Xanthomonas citri subsp. citri Aw12879]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References