Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 4151772..4152280 Replicon chromosome
Accession NZ_LS483452
Organism Shewanella benthica strain DB21MT-2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag SHEWBE_RS18925 Protein ID WP_112353870.1
Coordinates 4151772..4152032 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A330M9Z2
Locus tag SHEWBE_RS18930 Protein ID WP_040572210.1
Coordinates 4152029..4152280 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SHEWBE_RS18900 4147359..4148720 + 1362 WP_172605723.1 Na+/H+ antiporter NhaC family protein -
SHEWBE_RS18905 4148763..4149515 + 753 WP_112353867.1 pseudouridine synthase -
SHEWBE_RS18910 4150169..4150519 + 351 WP_112353868.1 type II toxin-antitoxin system RelE/ParE family toxin -
SHEWBE_RS18915 4150516..4150791 + 276 WP_112353869.1 helix-turn-helix domain-containing protein -
SHEWBE_RS18925 4151772..4152032 - 261 WP_112353870.1 Txe/YoeB family addiction module toxin Toxin
SHEWBE_RS18930 4152029..4152280 - 252 WP_040572210.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
SHEWBE_RS18935 4152778..4154934 - 2157 WP_112353871.1 S46 family peptidase -
SHEWBE_RS18940 4155203..4156402 - 1200 WP_112353872.1 amino acid permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10394.99 Da        Isoelectric Point: 10.1628

>T292596 WP_112353870.1 NZ_LS483452:c4152032-4151772 [Shewanella benthica]
MKLTFATKAWENYLYWQTTDKKMLKRINTLIKEIQRSPYSGIGKPEPLKHGLAGYWSRRINDEHRIVYKYQDDTILIAQL
RYHYST

Download         Length: 261 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9195.45 Da        Isoelectric Point: 4.2837

>AT292596 WP_040572210.1 NZ_LS483452:c4152280-4152029 [Shewanella benthica]
MDAISYTSARANLASTMAQVCNDHAPIIITRKSEAPVVMMSLEDYQAMEETTYLLRSPANARYLLESIAELEAGKGTERE
LLE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A330M9Z2

References