Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 2548471..2549381 Replicon chromosome
Accession NZ_LS483452
Organism Shewanella benthica strain DB21MT-2

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag SHEWBE_RS11710 Protein ID WP_112352761.1
Coordinates 2548471..2548932 (-) Length 154 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag SHEWBE_RS11715 Protein ID WP_112352762.1
Coordinates 2548929..2549381 (-) Length 151 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SHEWBE_RS11685 2544132..2544509 - 378 WP_112352757.1 hypothetical protein -
SHEWBE_RS11695 2545151..2546071 + 921 WP_112352759.1 diguanylate cyclase -
SHEWBE_RS11700 2546332..2547774 + 1443 WP_112354143.1 aspartate ammonia-lyase -
SHEWBE_RS11705 2548168..2548479 + 312 WP_112352760.1 hypothetical protein -
SHEWBE_RS11710 2548471..2548932 - 462 WP_112352761.1 RES family NAD+ phosphorylase Toxin
SHEWBE_RS11715 2548929..2549381 - 453 WP_112352762.1 DUF2384 domain-containing protein Antitoxin
SHEWBE_RS11720 2549592..2550263 + 672 WP_112352763.1 protein-disulfide isomerase -
SHEWBE_RS11725 2550722..2551675 + 954 WP_112352764.1 transcription termination factor Rho -
SHEWBE_RS11730 2551709..2552128 + 420 WP_112352765.1 VOC family protein -
SHEWBE_RS11735 2552394..2553770 + 1377 WP_112352766.1 response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(4-139)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(97-147)


Sequences

Toxin        


Download         Length: 154 a.a.        Molecular weight: 17316.55 Da        Isoelectric Point: 4.3824

>T292595 WP_112352761.1 NZ_LS483452:c2548932-2548471 [Shewanella benthica]
MITAYRIVKKKWAGNAFDGEGARIYGGRWNSRGQSCLYLAGSESLAILEILVHLDNAQQITHYALFTVELDEKDIMLLDH
DSLPHNWQEDPAPADTADLGDEWLNSQSSLALCVPSSIVTRERIFLLNVDHPAFDNMMDTKVELEFSMDTRLF

Download         Length: 462 bp

Antitoxin


Download         Length: 151 a.a.        Molecular weight: 16285.60 Da        Isoelectric Point: 9.7780

>AT292595 WP_112352762.1 NZ_LS483452:c2549381-2548929 [Shewanella benthica]
MAITNVFTPASAANKVIGFWQSVGVPARGASLYEALHTGLPFEVYAKLAKVSGIEKSELASATVIASATLQRRAKAGKFN
RDESDRLYRFAEVYKSALDLFEGEGVDATRWLRNPVRGLGNKRPIDMLSTSAETEAVLNLIGRLEHGVFA

Download         Length: 453 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References