29257

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4679860..4680221 Replicon chromosome
Accession NC_020800
Organism Xanthomonas axonopodis Xac29-1

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XAC29_RS42955 Protein ID WP_005914328.1
Coordinates 4679860..4679994 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag XAC29_RS42960 Protein ID WP_003486606.1
Coordinates 4680069..4680221 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XAC29_RS42935 4674998..4676689 - 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -
XAC29_RS42940 4676881..4677915 - 1035 WP_011052671.1 MBL fold metallo-hydrolase -
XAC29_RS42945 4677954..4679243 - 1290 WP_015463705.1 tryptophan--tRNA ligase -
XAC29_RS42950 4679424..4679633 - 210 WP_003486601.1 CsbD family protein -
XAC29_RS42955 4679860..4679994 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XAC29_RS42960 4680069..4680221 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
XAC29_RS42965 4680328..4681251 - 924 WP_005927745.1 arginase -
XAC29_RS42970 4681572..4682024 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
XAC29_RS42975 4682088..4682447 + 360 WP_003486613.1 hypothetical protein -
XAC29_RS42980 4682544..4683461 + 918 WP_011052673.1 hypothetical protein -
XAC29_RS42985 4683458..4684000 + 543 WP_003486615.1 GTPase -
XAC29_RS42990 4684438..4685121 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T29257 WP_005914328.1 NC_020800:c4679994-4679860 [Xanthomonas axonopodis Xac29-1]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T29257 NC_020800:c4679994-4679860 [Xanthomonas axonopodis Xac29-1]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT29257 WP_003486606.1 NC_020800:c4680221-4680069 [Xanthomonas axonopodis Xac29-1]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT29257 NC_020800:c4680221-4680069 [Xanthomonas axonopodis Xac29-1]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References