Detailed information of TA system TA029256

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2843917..2844473
• Replicon: chromosome
• Accession: NC_020800
• Organism: Xanthomonas axonopodis Xac29-1

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: XAC29_RS35175
• Protein ID: WP_011051576.1
• Coordinates: 2843917..2844207 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: M4UBZ0
• Locus tag: XAC29_RS35180
• Protein ID: WP_004541313.1
• Coordinates: 2844195..2844473 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XAC29_RS35150	2839260..2839781	+	522	WP_011051570.1	hypothetical protein	-
XAC29_RS48690	2840220..2840360	-	141	WP_157860651.1	hypothetical protein	-
XAC29_RS48695	2840646..2841602	-	957	WP_011051571.1	hypothetical protein	-
XAC29_RS35160	2841669..2842802	-	1134	Protein_2428	IS5 family transposase	-
XAC29_RS47780	2842842..2843006	-	165	Protein_2429	integrase core domain-containing protein	-
XAC29_RS35165	2843150..2843329	-	180	WP_015463309.1	hypothetical protein	-
XAC29_RS35170	2843600..2843914	-	315	WP_015463310.1	hypothetical protein	-
XAC29_RS35175	2843917..2844207	-	291	WP_011051576.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
XAC29_RS35180	2844195..2844473	-	279	WP_004541313.1	CopG family ribbon-helix-helix protein	Antitoxin
XAC29_RS35185	2844643..2845911	-	1269	Protein_2434	transposase	-
XAC29_RS35195	2845960..2847185	+	1226	Protein_2435	IS3 family transposase	-
XAC29_RS35200	2847804..2848760	+	957	WP_015463313.1	recombinase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2837079..2862606	25527
	-	inside	IScluster/Tn	-	-	2841669..2847185	5516

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10831.41 Da
• Isoelectric Point: 9.9308

>T29256 WP_011051576.1 NC_020800:c2844207-2843917 [Xanthomonas axonopodis Xac29-1]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T29256 NC_020800:c2844207-2843917 [Xanthomonas axonopodis Xac29-1]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10810.11 Da
• Isoelectric Point: 4.9736

>AT29256 WP_004541313.1 NC_020800:c2844473-2844195 [Xanthomonas axonopodis Xac29-1]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT29256 NC_020800:c2844473-2844195 [Xanthomonas axonopodis Xac29-1]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: M4UBZ0