Detailed information of TA system TA029255

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN-MazE
• Location: 2576929..2577562
• Replicon: chromosome
• Accession: NC_020800
• Organism: Xanthomonas axonopodis Xac29-1

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: XAC29_RS33970
• Protein ID: WP_015463212.1
• Coordinates: 2576929..2577342 (-)
• Length: 138 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: M4TWF0
• Locus tag: XAC29_RS33975
• Protein ID: WP_015463213.1
• Coordinates: 2577329..2577562 (-)
• Length: 78 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XAC29_RS33960	2572621..2574801	+	2181	WP_011051394.1	TonB-dependent siderophore receptor	-
XAC29_RS33965	2575010..2576524	+	1515	WP_015463210.1	conjugal transfer protein TraG N-terminal domain-containing protein	-
XAC29_RS46545	2576540..2576902	-	363	WP_015463211.1	DUF3742 family protein	-
XAC29_RS33970	2576929..2577342	-	414	WP_015463212.1	PIN domain-containing protein	Toxin
XAC29_RS33975	2577329..2577562	-	234	WP_015463213.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
XAC29_RS33980	2577820..2578851	+	1032	WP_040107627.1	DUF4917 family protein	-
XAC29_RS33985	2578984..2579382	-	399	WP_099521978.1	hypothetical protein	-
XAC29_RS33990	2579834..2580409	+	576	WP_011051400.1	sigma-70 family RNA polymerase sigma factor	-
XAC29_RS33995	2580390..2581439	+	1050	WP_011051401.1	FecR domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (8-119)

Antitoxin

• SpoVT-AbrB domain (5-45)

Sequences

Toxin

Protein

• Length: 138 a.a.
• Molecular weight: 15221.65 Da
• Isoelectric Point: 6.3225

>T29255 WP_015463212.1 NC_020800:c2577342-2576929 [Xanthomonas axonopodis Xac29-1]
MAAGKGKVFLDSNVVLYLLSEDAVKADGAEALLQRRPVISVQVLNEVTHVCVRKLKMGWDEVGQFLALVRSFCKIVPLTV
DVHDRARQLAERHQLSFYDACIVAAAAIEGCQTLYSEDMHHGLIIEESLSIRNPFNV

Nucleotide

• Length: 414 bp

>T29255 NC_020800:c2577342-2576929 [Xanthomonas axonopodis Xac29-1]
ATGGCCGCGGGTAAGGGCAAAGTGTTTCTCGACAGCAACGTGGTGCTCTACCTGCTGTCGGAGGATGCGGTGAAGGCGGA
CGGCGCGGAGGCATTGCTGCAGCGCAGGCCCGTCATCAGTGTGCAGGTGCTCAATGAAGTGACCCACGTCTGCGTTCGCA
AGCTCAAGATGGGCTGGGACGAAGTCGGGCAGTTCCTTGCGTTGGTGCGATCGTTCTGCAAGATAGTGCCTCTGACGGTC
GATGTTCACGACCGTGCGCGCCAGCTGGCGGAGCGGCACCAATTGTCGTTCTACGACGCGTGCATCGTGGCGGCGGCCGC
CATCGAAGGGTGCCAGACCCTCTACTCCGAAGACATGCACCACGGCCTCATCATCGAAGAGAGCCTGTCGATTCGGAACC
CGTTCAACGTCTGA

Antitoxin

Protein

• Length: 78 a.a.
• Molecular weight: 8663.97 Da
• Isoelectric Point: 8.7848

>AT29255 WP_015463213.1 NC_020800:c2577562-2577329 [Xanthomonas axonopodis Xac29-1]
MQVAKWGNSLAVRLPSSLVEALELREGDDIEIVVDDPRLFAVRKKPGPEAMLERLRAFRGKLPADFKFNRDEANGRG

Nucleotide

• Length: 234 bp

>AT29255 NC_020800:c2577562-2577329 [Xanthomonas axonopodis Xac29-1]
ATGCAAGTCGCGAAGTGGGGTAACAGCCTGGCGGTGCGCCTGCCGTCCAGTCTGGTGGAAGCGCTGGAACTGCGCGAGGG
CGACGACATCGAGATCGTCGTCGATGATCCGCGATTGTTCGCGGTGCGCAAGAAGCCGGGTCCGGAGGCCATGTTGGAGC
GGCTGCGTGCCTTCCGGGGCAAGTTGCCCGCAGATTTCAAGTTCAACCGGGACGAGGCCAATGGCCGCGGGTAA

Structures

Antitoxin

• AlphaFold DB: M4TWF0