Detailed information of TA system TA029254

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 99494..100038
• Replicon: chromosome
• Accession: NC_020800
• Organism: Xanthomonas axonopodis Xac29-1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: H8FI26
• Locus tag: XAC29_RS23185
• Protein ID: WP_003487886.1
• Coordinates: 99739..100038 (+)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: H8FI25
• Locus tag: XAC29_RS23180
• Protein ID: WP_003487884.1
• Coordinates: 99494..99751 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XAC29_RS23165	94613..96094	-	1482	WP_015462698.1	ribonuclease H-like domain-containing protein	-
XAC29_RS23170	96091..98586	-	2496	WP_015462699.1	DEAD/DEAH box helicase	-
XAC29_RS23175	98764..99426	+	663	WP_005912558.1	hemolysin III family protein	-
XAC29_RS23180	99494..99751	+	258	WP_003487884.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
XAC29_RS23185	99739..100038	+	300	WP_003487886.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
XAC29_RS23190	100218..101117	-	900	WP_011050073.1	SDR family NAD(P)-dependent oxidoreductase	-
XAC29_RS23195	101177..101914	-	738	WP_003487890.1	SDR family oxidoreductase	-
XAC29_RS23200	102040..102951	+	912	WP_011050074.1	LysR family transcriptional regulator	-
XAC29_RS23205	103117..104190	-	1074	WP_040107715.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11231.97 Da
• Isoelectric Point: 9.7235

>T29254 WP_003487886.1 NC_020800:99739-100038 [Xanthomonas axonopodis Xac29-1]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFGHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VVVHVMRSERALRGNRLSR

Nucleotide

• Length: 300 bp

>T29254 NC_020800:99739-100038 [Xanthomonas axonopodis Xac29-1]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATTGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGGGCACGTTGAGCAATTGATCGAACACCCGGACAGCGGAAGCCGACCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGGTGGTGCACGTCATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9683.21 Da
• Isoelectric Point: 9.8274

>AT29254 WP_003487884.1 NC_020800:99494-99751 [Xanthomonas axonopodis Xac29-1]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQARHRM
ARWLK

Nucleotide

• Length: 258 bp

>AT29254 NC_020800:99494-99751 [Xanthomonas axonopodis Xac29-1]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGTGGAGAAATGGCAGTCGCGGAAGGCCGTACGCTGAGCCATGAACAGGCACGGCACCGCATG
GCGCGATGGCTGAAATAA

Structures

Toxin

• AlphaFold DB: H8FI26

Antitoxin

• AlphaFold DB: H8FI25