Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 687244..688712 Replicon chromosome
Accession NZ_LS483406
Organism Stenotrophomonas maltophilia strain NCTC10498

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag DQN96_RS03175 Protein ID WP_157803285.1
Coordinates 687244..688113 (-) Length 290 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag DQN96_RS03180 Protein ID WP_032966430.1
Coordinates 688110..688712 (-) Length 201 a.a.

Genomic Context

DQN96_RS03170DQN96_RS03200DQN96_RS03205DQN96_RS03210DQN96_RS03155DQN96_RS03160DQN96_RS03165DQN96_RS03175DQN96_RS03180DQN96_RS03190DQN96_RS03195
Location: 686272..687090 (819 bp)
Type: Others
Protein ID: WP_060381104.1
Location: 691336..691782 (447 bp)
Type: Others
Protein ID: WP_004143635.1
Location: 691797..692765 (969 bp)
Type: Others
Protein ID: WP_012479154.1
Location: 692762..693025 (264 bp)
Type: Others
Protein ID: WP_005412242.1
Location: 683422..684000 (579 bp)
Type: Others
Protein ID: WP_100438875.1
Location: 684111..684479 (369 bp)
Type: Others
Protein ID: WP_012479149.1
Location: 684469..686190 (1722 bp)
Type: Others
Protein ID: WP_049459446.1
Location: 687244..688113 (870 bp)
Type: Toxin
Protein ID: WP_157803285.1
Location: 688110..688712 (603 bp)
Type: Antitoxin
Protein ID: WP_032966430.1
Location: 689463..689942 (480 bp)
Type: Others
Protein ID: WP_100438877.1
Location: 690260..691012 (753 bp)
Type: Others
Protein ID: WP_100438888.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
DQN96_RS03155683422..684000-579WP_100438875.1metal-dependent hydrolase-
DQN96_RS03160684111..684479-369WP_012479149.1YraN family protein-
DQN96_RS03165684469..686190-1722WP_049459446.1penicillin-binding protein activator-
DQN96_RS03170686272..687090+819WP_060381104.116S rRNA (cytidine(1402)-2'-O)-methyltransferase-
DQN96_RS03175687244..688113-870WP_157803285.1nucleotidyl transferase AbiEii/AbiGii toxin family proteinToxin
DQN96_RS03180688110..688712-603WP_032966430.1type IV toxin-antitoxin system AbiEi family antitoxin domain-containing proteinAntitoxin
DQN96_RS03190689463..689942-480WP_100438877.1DM13 domain-containing protein-
DQN96_RS03195690260..691012-753WP_100438888.1NRDE family protein-
DQN96_RS03200691336..691782+447WP_004143635.1division/cell wall cluster transcriptional repressor MraZ-
DQN96_RS03205691797..692765+969WP_012479154.116S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH-
DQN96_RS03210692762..693025+264WP_005412242.1cell division protein FtsL-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--674408..68994215534


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(40-268)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(12-53)


Sequences

Toxin        


Download         Length: 290 a.a.        Molecular weight: 32579.23 Da        Isoelectric Point: 6.3012

>T292504 WP_157803285.1 NZ_LS483406:c688113-687244 [Stenotrophomonas maltophilia]
VTHSPPLPQRVASIRQRLLDLARSRGEDFQFVLDRFAVERLLYRLSASRYRDQFLLKGAMLFAVWFDAPHRPTRDADFLR
FGSADPDHLLHIARSLCAIPDDDGLCFDPGSIAIEATREEAEYEGLRIRLTAHLGRSRCHVQWDVGFGDAVTPPPPEIAY
PVMLDGFPLPCLHVYPRETVFAEKLEAIAALGIANSRMKDFFDLLALVREDAMDRPHLVAAIGATFDRRRTPAPPPLPYG
LTQSFAADTQKQTQWRAFLRRNRLIAPDLSSVIAEIADYLDTLDTTVQS

Download         Length: 870 bp

Antitoxin


Download         Length: 201 a.a.        Molecular weight: 22331.07 Da        Isoelectric Point: 11.2557

>AT292504 WP_032966430.1 NZ_LS483406:c688712-688110 [Stenotrophomonas maltophilia]
MGNAEANARKLLRRAGTLRARELVTAGIARAQLTRLVEAGALIRLSRGVYALAERNSDDTDDGLRIIAERLPHPRLCLLS
ALRLHGLTTQAPFERWVSIGNSDRVPRIDWPPLRVVRMSAKTLNAGLEERRVGKRLIYVSNVAKTVVDCFKFRNLVGLDV
AIEALRDALHSRATTPDALMEYARICRVARLMRPYLDALA

Download         Length: 603 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References