Detailed information of TA system TA292504

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 687244..688712
• Replicon: chromosome
• Accession: NZ_LS483406
• Organism: Stenotrophomonas maltophilia strain NCTC10498

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: DQN96_RS03175
• Protein ID: WP_157803285.1
• Coordinates: 687244..688113 (-)
• Length: 290 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: DQN96_RS03180
• Protein ID: WP_032966430.1
• Coordinates: 688110..688712 (-)
• Length: 201 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DQN96_RS03155	683422..684000	-	579	WP_100438875.1	metal-dependent hydrolase	-
DQN96_RS03160	684111..684479	-	369	WP_012479149.1	YraN family protein	-
DQN96_RS03165	684469..686190	-	1722	WP_049459446.1	penicillin-binding protein activator	-
DQN96_RS03170	686272..687090	+	819	WP_060381104.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
DQN96_RS03175	687244..688113	-	870	WP_157803285.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
DQN96_RS03180	688110..688712	-	603	WP_032966430.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
DQN96_RS03190	689463..689942	-	480	WP_100438877.1	DM13 domain-containing protein	-
DQN96_RS03195	690260..691012	-	753	WP_100438888.1	NRDE family protein	-
DQN96_RS03200	691336..691782	+	447	WP_004143635.1	division/cell wall cluster transcriptional repressor MraZ	-
DQN96_RS03205	691797..692765	+	969	WP_012479154.1	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	-
DQN96_RS03210	692762..693025	+	264	WP_005412242.1	cell division protein FtsL	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	674408..689942	15534

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (40-268)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (12-53)

Sequences

Toxin

Protein

• Length: 290 a.a.
• Molecular weight: 32579.23 Da
• Isoelectric Point: 6.3012

>T292504 WP_157803285.1 NZ_LS483406:c688113-687244 [Stenotrophomonas maltophilia]
VTHSPPLPQRVASIRQRLLDLARSRGEDFQFVLDRFAVERLLYRLSASRYRDQFLLKGAMLFAVWFDAPHRPTRDADFLR
FGSADPDHLLHIARSLCAIPDDDGLCFDPGSIAIEATREEAEYEGLRIRLTAHLGRSRCHVQWDVGFGDAVTPPPPEIAY
PVMLDGFPLPCLHVYPRETVFAEKLEAIAALGIANSRMKDFFDLLALVREDAMDRPHLVAAIGATFDRRRTPAPPPLPYG
LTQSFAADTQKQTQWRAFLRRNRLIAPDLSSVIAEIADYLDTLDTTVQS

Nucleotide

• Length: 870 bp

Antitoxin

Protein

• Length: 201 a.a.
• Molecular weight: 22331.07 Da
• Isoelectric Point: 11.2557

>AT292504 WP_032966430.1 NZ_LS483406:c688712-688110 [Stenotrophomonas maltophilia]
MGNAEANARKLLRRAGTLRARELVTAGIARAQLTRLVEAGALIRLSRGVYALAERNSDDTDDGLRIIAERLPHPRLCLLS
ALRLHGLTTQAPFERWVSIGNSDRVPRIDWPPLRVVRMSAKTLNAGLEERRVGKRLIYVSNVAKTVVDCFKFRNLVGLDV
AIEALRDALHSRATTPDALMEYARICRVARLMRPYLDALA

Nucleotide

• Length: 603 bp