Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 263243..263891 Replicon chromosome
Accession NZ_LS483406
Organism Stenotrophomonas maltophilia strain NCTC10498

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag DQN96_RS01215 Protein ID WP_005407702.1
Coordinates 263243..263548 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag DQN96_RS01220 Protein ID WP_005407703.1
Coordinates 263589..263891 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQN96_RS01180 258529..259377 + 849 WP_062606017.1 SPOR domain-containing protein -
DQN96_RS01195 259971..260642 - 672 WP_005407700.1 hypothetical protein -
DQN96_RS01200 260733..262238 - 1506 WP_005407701.1 hypothetical protein -
DQN96_RS01215 263243..263548 + 306 WP_005407702.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DQN96_RS01220 263589..263891 + 303 WP_005407703.1 putative addiction module antidote protein Antitoxin
DQN96_RS01225 264126..264448 - 323 Protein_237 hypothetical protein -
DQN96_RS01230 264529..264936 - 408 WP_043035194.1 hypothetical protein -
DQN96_RS01235 265531..266301 + 771 WP_005411960.1 DUF3011 domain-containing protein -
DQN96_RS01240 266326..266673 - 348 WP_005411961.1 hypothetical protein -
DQN96_RS01245 266804..267724 + 921 WP_100438271.1 arginase -
DQN96_RS01250 267885..268022 + 138 WP_005407710.1 entericidin A/B family lipoprotein -
DQN96_RS01255 268229..268450 + 222 WP_004153772.1 CsbD family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-90)

Antitoxin

Cro/C1-type helix-turn-helix domain

(43-95)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11444.15 Da        Isoelectric Point: 10.9897

>T292503 WP_005407702.1 NZ_LS483406:263243-263548 [Stenotrophomonas maltophilia]
MKIQRTRQFATWIDALKDVTARARILARIGRLAEGHPGDHRYLADGVSELRIDAGPGYRVYYTQRGRQLVILLVGGDKGS
QQRDIEKAKEIARALRASNWL

Download         Length: 306 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10703.27 Da        Isoelectric Point: 7.2780

>AT292503 WP_005407703.1 NZ_LS483406:263589-263891 [Stenotrophomonas maltophilia]
MAIKKKVELEAFDVAEHLHTPKEMAAYLDACIEESDGDSAFIAKALGDIARAQGMSKVARAAGLSRESLYRALSGERSPD
FSTILKVTRALGVRLHASAA

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References