Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB(toxin)
Location 309037..309495 Replicon chromosome
Accession NZ_LS483396
Organism Micrococcus luteus NCTC 2665

Toxin (Protein)


Gene name relE Uniprot ID C5CBH3
Locus tag DQN81_RS01375 Protein ID WP_010080486.1
Coordinates 309037..309291 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID C5CBH4
Locus tag DQN81_RS01380 Protein ID WP_010080485.1
Coordinates 309292..309495 (-) Length 68 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQN81_RS01340 304468..305166 - 699 WP_010080494.1 aquaporin Z -
DQN81_RS11755 305333..305854 - 522 WP_010080493.1 hypothetical protein -
DQN81_RS01350 306113..306838 + 726 WP_029248323.1 MSMEG_4193 family putative phosphomutase -
DQN81_RS01355 306835..307377 + 543 WP_010080490.1 DUF3090 domain-containing protein -
DQN81_RS01360 307377..308159 + 783 WP_010080489.1 SCO1664 family protein -
DQN81_RS01370 308469..309035 - 567 WP_010080487.1 mismatch-specific DNA-glycosylase -
DQN81_RS01375 309037..309291 - 255 WP_010080486.1 Txe/YoeB family addiction module toxin Toxin
DQN81_RS01380 309292..309495 - 204 WP_010080485.1 antitoxin Antitoxin
DQN81_RS01385 309656..310999 + 1344 WP_012751024.1 IS256-like element ISMlu11 family transposase -
DQN81_RS01390 311030..311365 + 336 Protein_270 transposase -
DQN81_RS01395 311470..312723 - 1254 WP_010078638.1 IS256-like element ISMlu1 family transposase -
DQN81_RS01400 313246..313959 + 714 WP_010080482.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9795.09 Da        Isoelectric Point: 6.7156

>T292497 WP_010080486.1 NZ_LS483396:c309291-309037 [Micrococcus luteus NCTC 2665]
MRLVSDRSAWDDCTHWQTTDRKVLQRINTLIDAALRDPLDGIGKPEQLKYGAAGAWSRRITEEHRLVYLVDGEDLIILQA
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7374.33 Da        Isoelectric Point: 4.5007

>AT292497 WP_010080485.1 NZ_LS483396:c309495-309292 [Micrococcus luteus NCTC 2665]
VPPEFDLADWYISRHHIAPEEAPMSISASEARKTLFPLIERVTADRDAVEIVSRKGNAVLMPADGDA

Download         Length: 204 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB C5CBH3

Antitoxin

Source ID Structure
AlphaFold DB C5CBH4

References