Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/YoeB(toxin)
Location 309037..309495 Replicon chromosome
Accession NZ_LS483396
Organism Micrococcus luteus NCTC 2665

Toxin (Protein)


Gene name relE Uniprot ID C5CBH3
Locus tag DQN81_RS01375 Protein ID WP_010080486.1
Coordinates 309037..309291 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID C5CBH4
Locus tag DQN81_RS01380 Protein ID WP_010080485.1
Coordinates 309292..309495 (-) Length 68 a.a.

Genomic Context


DQN81_RS01350DQN81_RS01355DQN81_RS01360DQN81_RS01385DQN81_RS01390DQN81_RS01400DQN81_RS01340DQN81_RS11755DQN81_RS01370DQN81_RS01375DQN81_RS01380DQN81_RS01395
Location: 306113..306838 (726 bp)
Type: Others
Protein ID: WP_029248323.1
Location: 306835..307377 (543 bp)
Type: Others
Protein ID: WP_010080490.1
Location: 307377..308159 (783 bp)
Type: Others
Protein ID: WP_010080489.1
Location: 309656..310999 (1344 bp)
Type: Others
Protein ID: WP_012751024.1
Location: 311030..311365 (336 bp)
Type: Others
Protein ID: Protein_270
Location: 313246..313959 (714 bp)
Type: Others
Protein ID: WP_010080482.1
Location: 304468..305166 (699 bp)
Type: Others
Protein ID: WP_010080494.1
Location: 305333..305854 (522 bp)
Type: Others
Protein ID: WP_010080493.1
Location: 308469..309035 (567 bp)
Type: Others
Protein ID: WP_010080487.1
Location: 309037..309291 (255 bp)
Type: Toxin
Protein ID: WP_010080486.1
Location: 309292..309495 (204 bp)
Type: Antitoxin
Protein ID: WP_010080485.1
Location: 311470..312723 (1254 bp)
Type: Others
Protein ID: WP_010078638.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
DQN81_RS01340304468..305166-699WP_010080494.1aquaporin Z-
DQN81_RS11755305333..305854-522WP_010080493.1hypothetical protein-
DQN81_RS01350306113..306838+726WP_029248323.1MSMEG_4193 family putative phosphomutase-
DQN81_RS01355306835..307377+543WP_010080490.1DUF3090 domain-containing protein-
DQN81_RS01360307377..308159+783WP_010080489.1SCO1664 family protein-
DQN81_RS01370308469..309035-567WP_010080487.1mismatch-specific DNA-glycosylase-
DQN81_RS01375309037..309291-255WP_010080486.1Txe/YoeB family addiction module toxinToxin
DQN81_RS01380309292..309495-204WP_010080485.1antitoxinAntitoxin
DQN81_RS01385309656..310999+1344WP_012751024.1IS256-like element ISMlu11 family transposase-
DQN81_RS01390311030..311365+336Protein_270transposase-
DQN81_RS01395311470..312723-1254WP_010078638.1IS256-like element ISMlu1 family transposase-
DQN81_RS01400313246..313959+714WP_010080482.1SUMF1/EgtB/PvdO family nonheme iron enzyme-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(7-84)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 85 a.a.        Molecular weight: 9795.09 Da        Isoelectric Point: 6.7156

>T292497 WP_010080486.1 NZ_LS483396:c309291-309037 [Micrococcus luteus NCTC 2665]
MRLVSDRSAWDDCTHWQTTDRKVLQRINTLIDAALRDPLDGIGKPEQLKYGAAGAWSRRITEEHRLVYLVDGEDLIILQA
RYHY

Download         Length: 255 bp


Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7374.33 Da        Isoelectric Point: 4.5007

>AT292497 WP_010080485.1 NZ_LS483396:c309495-309292 [Micrococcus luteus NCTC 2665]
VPPEFDLADWYISRHHIAPEEAPMSISASEARKTLFPLIERVTADRDAVEIVSRKGNAVLMPADGDA

Download         Length: 204 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBC5CBH3


Antitoxin

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Source
ID
Structure
AlphaFold DBC5CBH4

References