Detailed information of TA system TA292495

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 4333792..4334333
• Replicon: chromosome
• Accession: NZ_LS483395
• Organism: Achromobacter xylosoxidans strain NCTC10808

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: DQO23_RS19850
• Protein ID: WP_026384571.1
• Coordinates: 4333792..4334067 (-)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: DQO23_RS19855
• Protein ID: WP_024069590.1
• Coordinates: 4334067..4334333 (-)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DQO23_RS19830	4329744..4330667	+	924	WP_006385014.1	ABC transporter permease	-
DQO23_RS19835	4330673..4331539	+	867	WP_024069588.1	ABC transporter permease	-
DQO23_RS19840	4331597..4333336	+	1740	WP_024069589.1	hypothetical protein	-
DQO23_RS19845	4333349..4333786	+	438	WP_020928528.1	acetyltransferase	-
DQO23_RS19850	4333792..4334067	-	276	WP_026384571.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
DQO23_RS19855	4334067..4334333	-	267	WP_024069590.1	ribbon-helix-helix domain-containing protein	Antitoxin
DQO23_RS19860	4334580..4335107	+	528	WP_024069591.1	sigma-70 family RNA polymerase sigma factor	-
DQO23_RS19865	4335193..4336149	+	957	WP_054498804.1	FecR domain-containing protein	-
DQO23_RS19870	4336409..4338835	+	2427	WP_070543066.1	TonB-dependent receptor	-
DQO23_RS19875	4338888..4339094	-	207	WP_006385007.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (8-45)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10710.42 Da
• Isoelectric Point: 10.4170

>T292495 WP_026384571.1 NZ_LS483395:c4334067-4333792 [Achromobacter xylosoxidans]
MEMKWTSKALSDLARLHEFLAAVNRPAAVRAVQALVKASSVLPTNSRIGEQLFQFEPREVRRILVGEYEIRYEIRDSIIY
VLRLWHTRENR

Nucleotide

• Length: 276 bp

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 9699.04 Da
• Isoelectric Point: 4.5720

>AT292495 WP_024069590.1 NZ_LS483395:c4334333-4334067 [Achromobacter xylosoxidans]
MSPATKVLTAHVPLPLAEKVDQMAVRLDRSRGWIVKQALSAWIAQEEERDKLTEQALADVDAGRIVDDQAVQAWAESLGS
DQPLPLPR

Nucleotide

• Length: 267 bp