Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 1077094..1077667 Replicon chromosome
Accession NZ_LS483395
Organism Achromobacter xylosoxidans strain NCTC10808

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag DQO23_RS04950 Protein ID WP_111727627.1
Coordinates 1077290..1077667 (+) Length 126 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag DQO23_RS04945 Protein ID WP_054471260.1
Coordinates 1077094..1077303 (+) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQO23_RS04925 1072500..1073288 - 789 WP_024067852.1 helix-turn-helix transcriptional regulator -
DQO23_RS04930 1073387..1074313 + 927 WP_020924995.1 DMT family transporter -
DQO23_RS04935 1074326..1075144 - 819 WP_058207221.1 AAC(3) family N-acetyltransferase -
DQO23_RS04940 1075296..1076969 + 1674 WP_024067854.1 energy-dependent translational throttle protein EttA -
DQO23_RS04945 1077094..1077303 + 210 WP_054471260.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
DQO23_RS04950 1077290..1077667 + 378 WP_111727627.1 type II toxin-antitoxin system VapC family toxin Toxin
DQO23_RS04955 1077735..1078268 + 534 WP_024067855.1 isochorismatase family protein -
DQO23_RS04960 1078459..1078683 + 225 WP_006388976.1 glycine zipper 2TM domain-containing protein -
DQO23_RS04965 1078813..1079070 - 258 WP_006388977.1 cell division topological specificity factor MinE -
DQO23_RS04970 1079074..1079889 - 816 WP_006388978.1 septum site-determining protein MinD -
DQO23_RS04975 1080078..1080995 - 918 WP_024067857.1 septum site-determining protein MinC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(2-44)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 13876.14 Da        Isoelectric Point: 6.3721

>T292493 WP_111727627.1 NZ_LS483395:1077290-1077667 [Achromobacter xylosoxidans]
MILVDTSIWIDHLSDGEPCLVRLLEEESVLMHPFIAGELALGSLGRRDVVLGTMSLLPQVVRASHDEVMHFLHSERLFGK
GIGYVDLHLLASTRLTPGAALWTRDKRLQALATTLSLAVDPPRYH

Download         Length: 378 bp

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7521.62 Da        Isoelectric Point: 9.9435

>AT292493 WP_054471260.1 NZ_LS483395:1077094-1077303 [Achromobacter xylosoxidans]
VRTTVTLDDDLLELARTYTGVQETSALVTRALTQLVQKEAAKRLAKLGGSSPKLKPIPRRQTETCNDPG

Download         Length: 210 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References