Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 156313..156867 Replicon chromosome
Accession NZ_LS483395
Organism Achromobacter xylosoxidans strain NCTC10808

Toxin (Protein)


Gene name relE Uniprot ID A0A0D6FFH4
Locus tag DQO23_RS00730 Protein ID WP_006386989.1
Coordinates 156589..156867 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0D6FFH2
Locus tag DQO23_RS00725 Protein ID WP_024067400.1
Coordinates 156313..156519 (+) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQO23_RS00710 152955..153932 - 978 WP_024067397.1 tripartite tricarboxylate transporter substrate binding protein -
DQO23_RS00715 154125..154775 - 651 WP_024067398.1 hypothetical protein -
DQO23_RS00720 154774..156219 + 1446 WP_024067399.1 RNA polymerase factor sigma-54 -
DQO23_RS00725 156313..156519 + 207 WP_024067400.1 hypothetical protein Antitoxin
DQO23_RS00730 156589..156867 + 279 WP_006386989.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DQO23_RS00735 157046..157345 + 300 WP_006386990.1 (2Fe-2S)-binding protein -
DQO23_RS00740 157315..158235 - 921 WP_006386991.1 LysR family transcriptional regulator -
DQO23_RS00745 158349..159263 + 915 WP_024067401.1 DMT family transporter -
DQO23_RS00750 159688..160164 + 477 WP_006386993.1 bacterioferritin -
DQO23_RS00755 160249..160935 - 687 WP_006386994.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10370.91 Da        Isoelectric Point: 9.0854

>T292492 WP_006386989.1 NZ_LS483395:156589-156867 [Achromobacter xylosoxidans]
MLDVSWLQTAADDLAGIISYIAERSPQAARDLRQRIDNAVLSLARHPCRYRAGRVSGTRECVVHPNYVVVYRVTALAIEV
VNIVHARREYPP

Download         Length: 279 bp

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7729.62 Da        Isoelectric Point: 4.5026

>AT292492 WP_024067400.1 NZ_LS483395:156313-156519 [Achromobacter xylosoxidans]
MGPIPSSILSEFETEEQAVSYDRWFRAKVQASLDDPRPAVSHQRVMARIDAIIETACRRQLDPQDGEN

Download         Length: 207 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0D6FFH4

Antitoxin

Source ID Structure
AlphaFold DB A0A0D6FFH2

References