Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 300374..300978 Replicon chromosome
Accession NZ_LS483392
Organism Haemophilus influenzae strain NCTC11931

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DQM65_RS01590 Protein ID WP_111691059.1
Coordinates 300670..300978 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0Y7JSS2
Locus tag DQM65_RS01585 Protein ID WP_005661259.1
Coordinates 300374..300670 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQM65_RS01570 296140..297525 + 1386 WP_111691056.1 L-seryl-tRNA(Sec) selenium transferase -
DQM65_RS01575 297522..299381 + 1860 WP_111691057.1 selenocysteine-specific translation elongation factor -
DQM65_RS01580 299400..300254 + 855 WP_111691058.1 DUF3298 domain-containing protein -
DQM65_RS01585 300374..300670 + 297 WP_005661259.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
DQM65_RS01590 300670..300978 + 309 WP_111691059.1 type II toxin-antitoxin system YafQ family toxin Toxin
DQM65_RS01595 301035..304196 - 3162 WP_111691983.1 TonB-dependent hemoglobin/transferrin/lactoferrin family receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(7-100)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-93)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11881.61 Da        Isoelectric Point: 7.3187

>T292483 WP_111691059.1 NZ_LS483392:300670-300978 [Haemophilus influenzae]
MSEDKPLKVSYSKQFVRDLTDLAKRSPNVLIGSKYITAIHCLLNRLPLPENYQDHALVGEWKGYRDCHIQGDLVLIYQYV
IQDEFDELKFSRLNTHSQTALK

Download         Length: 309 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11015.37 Da        Isoelectric Point: 4.4297

>AT292483 WP_005661259.1 NZ_LS483392:300374-300670 [Haemophilus influenzae]
MALTNSSISFRTVEKTKLEAYQVIEQYGLTPSQVFNMFLAQIAKTRSIPVDLNYLRPNKETLAAIDELDSGNAESFFIEA
SENYSAEEFTKRILNGGQ

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0Y7JSS2

References