292464

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 61464..61956 Replicon chromosome
Accession NZ_LS483381
Organism Streptococcus sobrinus strain NCTC10921

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DQM69_RS00355 Protein ID WP_109982349.1
Coordinates 61690..61956 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DQM69_RS00350 Protein ID WP_109982348.1
Coordinates 61464..61697 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQM69_RS00330 56616..58163 + 1548 WP_109982346.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase -
DQM69_RS00335 58367..58906 - 540 WP_002959581.1 TetR/AcrR family transcriptional regulator -
DQM69_RS00340 59059..59580 + 522 WP_019769995.1 HXXEE domain-containing protein -
DQM69_RS00345 59906..61093 + 1188 WP_109982347.1 LysM peptidoglycan-binding domain-containing protein -
DQM69_RS00350 61464..61697 + 234 WP_109982348.1 RelB protein Antitoxin
DQM69_RS00355 61690..61956 + 267 WP_109982349.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DQM69_RS00360 62011..63825 + 1815 WP_109982350.1 hypothetical protein -
DQM69_RS00365 63985..65244 + 1260 WP_109982351.1 phosphoribosylamine--glycine ligase -
DQM69_RS00370 65241..65684 + 444 WP_019783927.1 DUF523 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10135.99 Da        Isoelectric Point: 10.5049

>T292464 WP_109982349.1 NZ_LS483381:61690-61956 [Streptococcus sobrinus]
MYKLVLSKAFIKQLSKLDKYTANSILVWLEKNIDGLDNPRQKGKALVGDLKGLWRYRVGNYRVICQIKDDQLVVVAVSGG
HRKEIYKK

Download         Length: 267 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8595.65 Da        Isoelectric Point: 4.1948

>AT292464 WP_109982348.1 NZ_LS483381:61464-61697 [Streptococcus sobrinus]
MPVISLRLNKEEEIFFKNYAHFTGKSLSELFKNALAEEIENQLDYKLGAEGVQALEADGGQTYSIAEARDMLGLDNV

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References