Detailed information of TA system TA292456

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 692967..694435
• Replicon: chromosome
• Accession: NZ_LS483377
• Organism: Stenotrophomonas maltophilia strain NCTC10258

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: DQN92_RS03135
• Protein ID: WP_197713298.1
• Coordinates: 692967..693716 (-)
• Length: 250 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: DQN92_RS03140
• Protein ID: WP_032966430.1
• Coordinates: 693833..694435 (-)
• Length: 201 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DQN92_RS03115	689079..689723	-	645	WP_111686876.1	metal-dependent hydrolase	-
DQN92_RS03120	689834..690202	-	369	WP_024957270.1	YraN family protein	-
DQN92_RS03125	690192..691913	-	1722	WP_111686878.1	penicillin-binding protein activator	-
DQN92_RS03130	691995..692813	+	819	WP_005412235.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
DQN92_RS03135	692967..693716	-	750	WP_197713298.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
DQN92_RS03140	693833..694435	-	603	WP_032966430.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
DQN92_RS03150	695186..695665	-	480	WP_005412238.1	DM13 domain-containing protein	-
DQN92_RS03160	695983..696735	-	753	WP_111687890.1	NRDE family protein	-
DQN92_RS03165	697059..697505	+	447	WP_111686881.1	division/cell wall cluster transcriptional repressor MraZ	-
DQN92_RS03170	697520..698488	+	969	WP_111686882.1	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	-
DQN92_RS03175	698485..698748	+	264	WP_005412242.1	cell division protein FtsL	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (2-228)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (12-53)

Sequences

Toxin

Protein

• Length: 250 a.a.
• Molecular weight: 27838.79 Da
• Isoelectric Point: 5.3302

>T292456 WP_197713298.1 NZ_LS483377:c693716-692967 [Stenotrophomonas maltophilia]
MLYRLSASRYRDQFLLKGAMLFAVWFDAPHRPTRDADFLRFGSADPDHLLHIARSLCAIPDDDGLCFDPGSIAIEATREE
AEYEGLRIRLTAHLGRSRCHVQWDVGFGDAVTPPPPEIAYPVMLDGFPLPCLHVYPRETVFAEKLEAIAALGIANSRMKD
FFDLLALVREDAMDRPHLVAAIGATFDRRGTPAPPPLPYGLTQSFAADTQKQTQWRAFLRRNRLIAPDLSSVIAEIADYL
DTLDTTVQS

Nucleotide

• Length: 750 bp

Antitoxin

Protein

• Length: 201 a.a.
• Molecular weight: 22331.07 Da
• Isoelectric Point: 11.2557

>AT292456 WP_032966430.1 NZ_LS483377:c694435-693833 [Stenotrophomonas maltophilia]
MGNAEANARKLLRRAGTLRARELVTAGIARAQLTRLVEAGALIRLSRGVYALAERNSDDTDDGLRIIAERLPHPRLCLLS
ALRLHGLTTQAPFERWVSIGNSDRVPRIDWPPLRVVRMSAKTLNAGLEERRVGKRLIYVSNVAKTVVDCFKFRNLVGLDV
AIEALRDALHSRATTPDALMEYARICRVARLMRPYLDALA

Nucleotide

• Length: 603 bp