Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 283221..283869 Replicon chromosome
Accession NZ_LS483377
Organism Stenotrophomonas maltophilia strain NCTC10258

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag DQN92_RS01275 Protein ID WP_005407702.1
Coordinates 283221..283526 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag DQN92_RS01280 Protein ID WP_005407703.1
Coordinates 283567..283869 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQN92_RS01245 279172..279963 - 792 WP_172459911.1 zinc-dependent peptidase -
DQN92_RS01250 279930..280208 - 279 WP_005411956.1 hypothetical protein -
DQN92_RS01255 280353..281321 + 969 WP_062606021.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
DQN92_RS01260 281318..282049 + 732 WP_005407698.1 type III pantothenate kinase -
DQN92_RS01265 282059..282913 + 855 WP_111686768.1 SPOR domain-containing protein -
DQN92_RS01275 283221..283526 + 306 WP_005407702.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DQN92_RS01280 283567..283869 + 303 WP_005407703.1 putative addiction module antidote protein Antitoxin
DQN92_RS01285 284127..284426 - 300 WP_111686769.1 hypothetical protein -
DQN92_RS01290 284507..284914 - 408 WP_005407705.1 hypothetical protein -
DQN92_RS01295 285509..286279 + 771 WP_005411960.1 DUF3011 domain-containing protein -
DQN92_RS01300 286304..286651 - 348 WP_005411961.1 hypothetical protein -
DQN92_RS01305 286782..287702 + 921 WP_005407709.1 arginase -
DQN92_RS01310 287863..288000 + 138 WP_005407710.1 entericidin A/B family lipoprotein -
DQN92_RS01315 288208..288429 + 222 WP_004153772.1 CsbD family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-90)

Antitoxin

Cro/C1-type helix-turn-helix domain

(43-95)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11444.15 Da        Isoelectric Point: 10.9897

>T292455 WP_005407702.1 NZ_LS483377:283221-283526 [Stenotrophomonas maltophilia]
MKIQRTRQFATWIDALKDVTARARILARIGRLAEGHPGDHRYLADGVSELRIDAGPGYRVYYTQRGRQLVILLVGGDKGS
QQRDIEKAKEIARALRASNWL

Download         Length: 306 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10703.27 Da        Isoelectric Point: 7.2780

>AT292455 WP_005407703.1 NZ_LS483377:283567-283869 [Stenotrophomonas maltophilia]
MAIKKKVELEAFDVAEHLHTPKEMAAYLDACIEESDGDSAFIAKALGDIARAQGMSKVARAAGLSRESLYRALSGERSPD
FSTILKVTRALGVRLHASAA

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References