Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 857431..857914 Replicon chromosome
Accession NZ_LS483368
Organism Streptococcus equi subsp. zooepidemicus strain NCTC6176

Toxin (Protein)


Gene name relE Uniprot ID A0A922NVR0
Locus tag DQM56_RS04170 Protein ID WP_021320634.1
Coordinates 857654..857914 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A922NW74
Locus tag DQM56_RS04165 Protein ID WP_012678125.1
Coordinates 857431..857652 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQM56_RS04140 853971..854234 + 264 WP_012678127.1 hypothetical protein -
DQM56_RS04145 854416..854871 - 456 WP_021320631.1 DUF1694 domain-containing protein -
DQM56_RS04150 855103..856410 + 1308 WP_012515409.1 phosphopyruvate hydratase -
DQM56_RS04155 856649..856738 + 90 WP_111677961.1 type I toxin-antitoxin system Fst family toxin -
DQM56_RS04160 856985..857221 - 237 Protein_779 transposase -
DQM56_RS04165 857431..857652 + 222 WP_012678125.1 hypothetical protein Antitoxin
DQM56_RS04170 857654..857914 + 261 WP_021320634.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DQM56_RS04175 857992..858968 + 977 Protein_782 IS3 family transposase -
DQM56_RS10090 858969..859223 + 255 Protein_783 HAD family hydrolase -
DQM56_RS04185 859693..862473 + 2781 WP_111710494.1 endonuclease/exonuclease/phosphatase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 857992..858507 515


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10258.78 Da        Isoelectric Point: 9.6925

>T292446 WP_021320634.1 NZ_LS483368:857654-857914 [Streptococcus equi subsp. zooepidemicus]
MYHIEYSKKAQKQIKKLDKQIQRLLFAWIDKHLEGTDNPRANGKGLAGNHANEWRYRIGDYRLICDIQDDKMVILALEFG
HRRDVY

Download         Length: 261 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8506.54 Da        Isoelectric Point: 4.6104

>AT292446 WP_012678125.1 NZ_LS483368:857431-857652 [Streptococcus equi subsp. zooepidemicus]
MGTVTIRLNQEEEIFFKSYAQLTGQSLSSLFKKALERDIEDEYDLKLYHQAYAEYKADPETISHADFKKELGL

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References