Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 844902..845385 Replicon chromosome
Accession NZ_LS483354
Organism Streptococcus equi subsp. zooepidemicus strain NCTC11606

Toxin (Protein)


Gene name relE Uniprot ID B4U2C0
Locus tag DQL13_RS04055 Protein ID WP_012515411.1
Coordinates 845125..845385 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID B4U2B9
Locus tag DQL13_RS04050 Protein ID WP_012515410.1
Coordinates 844902..845123 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL13_RS04025 841428..841703 + 276 WP_012515407.1 hypothetical protein -
DQL13_RS04030 841887..842342 - 456 WP_041785400.1 DUF1694 domain-containing protein -
DQL13_RS04035 842574..843881 + 1308 WP_012515409.1 phosphopyruvate hydratase -
DQL13_RS04040 844120..844209 + 90 WP_111677961.1 type I toxin-antitoxin system Fst family toxin -
DQL13_RS04045 844456..844692 - 237 Protein_750 transposase -
DQL13_RS04050 844902..845123 + 222 WP_012515410.1 hypothetical protein Antitoxin
DQL13_RS04055 845125..845385 + 261 WP_012515411.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DQL13_RS04060 845465..846441 + 977 Protein_753 IS3 family transposase -
DQL13_RS09915 846442..846696 + 255 Protein_754 HAD family hydrolase -
DQL13_RS04070 847166..849946 + 2781 WP_012515415.1 endonuclease/exonuclease/phosphatase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-86)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10275.81 Da        Isoelectric Point: 9.8428

>T292414 WP_012515411.1 NZ_LS483354:845125-845385 [Streptococcus equi subsp. zooepidemicus]
MYRIEYSKKAQKQIKKVDKQIQRLLFAWIDKYLEGTDNPRANGKGLAGNHANEWRYRIGDYRLICDIQDDKMVVLALEFG
HRRDVY

Download         Length: 261 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8536.57 Da        Isoelectric Point: 4.6104

>AT292414 WP_012515410.1 NZ_LS483354:844902-845123 [Streptococcus equi subsp. zooepidemicus]
MSTVTIRLNQEEEIFFKSYAQLTGQSLSSLFKKALERDIEDEYDLKIYHQAYAEYKADPETISHADFKKELGL

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB B4U2C0

Antitoxin

Source ID Structure
AlphaFold DB A0A380KCN4

References