Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 309322..309856 Replicon chromosome
Accession NZ_LS483346
Organism Streptococcus sanguinis strain NCTC11085

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DQM73_RS01660 Protein ID WP_002926081.1
Coordinates 309578..309856 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DQM73_RS01655 Protein ID WP_002905395.1
Coordinates 309322..309585 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQM73_RS01640 304787..305734 + 948 WP_002934498.1 WYL domain-containing protein -
DQM73_RS01645 305984..307330 + 1347 WP_002926086.1 DUF262 domain-containing protein -
DQM73_RS01650 307324..309213 + 1890 WP_002926083.1 DUF262 domain-containing HNH endonuclease family protein -
DQM73_RS01655 309322..309585 + 264 WP_002905395.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
DQM73_RS01660 309578..309856 + 279 WP_002926081.1 type II toxin-antitoxin system YafQ family toxin Toxin
DQM73_RS12315 309944..310096 + 153 WP_002926079.1 hypothetical protein -
DQM73_RS01665 310118..311359 + 1242 WP_002926077.1 aminopeptidase -
DQM73_RS01670 311454..311684 + 231 WP_002908679.1 GlsB/YeaQ/YmgE family stress response membrane protein -
DQM73_RS01675 311746..312378 - 633 WP_002926068.1 peptide deformylase -
DQM73_RS01685 312572..313741 + 1170 WP_002926066.1 MFS transporter -
DQM73_RS01690 313753..314481 + 729 WP_002926064.1 rRNA pseudouridine synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 305987..319123 13136


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-58)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 11018.96 Da        Isoelectric Point: 9.7659

>T292390 WP_002926081.1 NZ_LS483346:309578-309856 [Streptococcus sanguinis]
VLKIRYHKQFKKDFKLAMKRGLKAELLEEVLEFLIQEKELPAKYRDHQLTASKHFKGVRECHVQPDWLLVYKVDKEELIL
NLLRTGSHSDLF

Download         Length: 279 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9949.33 Da        Isoelectric Point: 4.3719

>AT292390 WP_002905395.1 NZ_LS483346:309322-309585 [Streptococcus sanguinis]
MSKTSMSIRLDSEVKEQAQQVFNSLGMDMTTAINIFLRQAIQYQGLPFDVRLDESRKLMEVLADLEQNRNMSQSFGSVSD
LMEDLRA

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References