Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelB(antitoxin)
Location 1806314..1806926 Replicon chromosome
Accession NZ_LS483342
Organism Streptococcus agalactiae strain NCTC11930

Toxin (Protein)


Gene name parE Uniprot ID A0A8G2N8L3
Locus tag DQL56_RS09505 Protein ID WP_000384860.1
Coordinates 1806591..1806926 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID Q8E7D2
Locus tag DQL56_RS09500 Protein ID WP_000259017.1
Coordinates 1806314..1806601 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL56_RS09450 1801406..1802266 - 861 WP_000477654.1 Rgg/GadR/MutR family transcriptional regulator -
DQL56_RS09470 1803109..1803390 - 282 WP_000052406.1 hypothetical protein -
DQL56_RS09475 1803424..1803810 - 387 WP_000259069.1 hypothetical protein -
DQL56_RS09480 1803795..1804475 - 681 WP_001865565.1 hypothetical protein -
DQL56_RS09485 1804448..1805008 - 561 WP_001865562.1 hypothetical protein -
DQL56_RS09490 1805008..1805415 - 408 WP_000749954.1 hypothetical protein -
DQL56_RS09495 1805517..1805807 - 291 WP_000078283.1 WXG100 family type VII secretion target -
DQL56_RS09500 1806314..1806601 + 288 WP_000259017.1 hypothetical protein Antitoxin
DQL56_RS09505 1806591..1806926 + 336 WP_000384860.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DQL56_RS09510 1807231..1807701 - 471 WP_000130119.1 hypothetical protein -
DQL56_RS09515 1807869..1809125 - 1257 WP_000122836.1 plasmid recombination protein -
DQL56_RS09520 1809442..1809876 - 435 WP_001220479.1 hypothetical protein -
DQL56_RS09525 1809912..1810787 - 876 WP_000421240.1 hypothetical protein -
DQL56_RS09535 1811087..1811728 - 642 WP_000591144.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-106)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13227.87 Da        Isoelectric Point: 4.5348

>T292385 WP_000384860.1 NZ_LS483342:1806591-1806926 [Streptococcus agalactiae]
MDYKKYQIIYAPDVLEKLKEIRDYISQNYSSTSGQRKMEQIINDIEKLEVFPEVGFDADEKYGSEISNYHSTRGYTLSKD
YIVLYHIEEEENSVVIDYLLPTRSDYMKLFK

Download         Length: 336 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10906.50 Da        Isoelectric Point: 4.7271

>AT292385 WP_000259017.1 NZ_LS483342:1806314-1806601 [Streptococcus agalactiae]
MVTVEKNRAVTFQANKELVSEAMTVLNKKNLTLSSALRLFLQNVVVTNEVDLLTEEELEKEKLFKQFQAEISKNIEDVRQ
GKFYTSEEVRAELGL

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A076Z4V6

References