Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) abiEi-abiEii/AbiEii-AbiEi
Location 161387..162819 Replicon chromosome
Accession NZ_LS483339
Organism Streptococcus thermophilus strain NCTC12958

Toxin (Protein)


Gene name abiEi Uniprot ID -
Locus tag DQL34_RS00960 Protein ID WP_111679138.1
Coordinates 161387..162232 (-) Length 282 a.a.

Antitoxin (Protein)


Gene name abiEii Uniprot ID F8LVV9
Locus tag DQL34_RS00965 Protein ID WP_014621283.1
Coordinates 162229..162819 (-) Length 197 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL34_RS00955 158499..161300 + 2802 WP_111679136.1 CHAP domain-containing protein -
DQL34_RS00960 161387..162232 - 846 WP_111679138.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
DQL34_RS00965 162229..162819 - 591 WP_014621283.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(33-258)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(6-50)


Sequences

Toxin        


Download         Length: 282 a.a.        Molecular weight: 32428.07 Da        Isoelectric Point: 5.0493

>T292383 WP_111679138.1 NZ_LS483339:c162232-161387 [Streptococcus thermophilus]
MNKAKLTALCHKISKNTGLTFNSVMTYYFLEVILKKLSQSTYSNHYIFKGGFLLSNVIGVESRSTVDIDFLFHQITLSED
TVKQQLKEILADSEEGISFVIQSITAIKESDDYGGYRATISCQLENIKQVIHLDIATGDVVTPQPITYDYKAIFDEDNFP
IIAYTIETILAEKLQTIYSRNFLNSRSKDFYDVYILSKLKKEDIDFIQLKNACQRTFSYRETELDFVKIIELLERFKSDP
IQNKQWQNYSKKYSYTKGISLADVLDEMISLITIIISTDFD

Download         Length: 846 bp

Antitoxin


Download         Length: 197 a.a.        Molecular weight: 23313.88 Da        Isoelectric Point: 7.8482

>AT292383 WP_014621283.1 NZ_LS483339:c162819-162229 [Streptococcus thermophilus]
MSKKEILFEFIENHNGIITYKDCKALKIPTIYLTRLEKEGILYRVEKGIFLTQNGDYDEYYFFQYRYPKAIFSYISALYL
QQFTDEIPQYFDVTIPRGYRFNTPPANLNIHSVSKEYSELGITLVKTPMGNEVRVYDLERIICDFVIHREKIDTELFVKT
LQHYGNYSKKNLTKLYEYATKMNTLDKVKQTLEVLV

Download         Length: 591 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB F8LVV9

References