Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | abiEi-abiEii/AbiEii-AbiEi |
Location | 161387..162819 | Replicon | chromosome |
Accession | NZ_LS483339 | ||
Organism | Streptococcus thermophilus strain NCTC12958 |
Toxin (Protein)
Gene name | abiEi | Uniprot ID | - |
Locus tag | DQL34_RS00960 | Protein ID | WP_111679138.1 |
Coordinates | 161387..162232 (-) | Length | 282 a.a. |
Antitoxin (Protein)
Gene name | abiEii | Uniprot ID | F8LVV9 |
Locus tag | DQL34_RS00965 | Protein ID | WP_014621283.1 |
Coordinates | 162229..162819 (-) | Length | 197 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
DQL34_RS00955 | 158499..161300 | + | 2802 | WP_111679136.1 | CHAP domain-containing protein | - |
DQL34_RS00960 | 161387..162232 | - | 846 | WP_111679138.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
DQL34_RS00965 | 162229..162819 | - | 591 | WP_014621283.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 282 a.a. Molecular weight: 32428.07 Da Isoelectric Point: 5.0493
>T292383 WP_111679138.1 NZ_LS483339:c162232-161387 [Streptococcus thermophilus]
MNKAKLTALCHKISKNTGLTFNSVMTYYFLEVILKKLSQSTYSNHYIFKGGFLLSNVIGVESRSTVDIDFLFHQITLSED
TVKQQLKEILADSEEGISFVIQSITAIKESDDYGGYRATISCQLENIKQVIHLDIATGDVVTPQPITYDYKAIFDEDNFP
IIAYTIETILAEKLQTIYSRNFLNSRSKDFYDVYILSKLKKEDIDFIQLKNACQRTFSYRETELDFVKIIELLERFKSDP
IQNKQWQNYSKKYSYTKGISLADVLDEMISLITIIISTDFD
MNKAKLTALCHKISKNTGLTFNSVMTYYFLEVILKKLSQSTYSNHYIFKGGFLLSNVIGVESRSTVDIDFLFHQITLSED
TVKQQLKEILADSEEGISFVIQSITAIKESDDYGGYRATISCQLENIKQVIHLDIATGDVVTPQPITYDYKAIFDEDNFP
IIAYTIETILAEKLQTIYSRNFLNSRSKDFYDVYILSKLKKEDIDFIQLKNACQRTFSYRETELDFVKIIELLERFKSDP
IQNKQWQNYSKKYSYTKGISLADVLDEMISLITIIISTDFD
Download Length: 846 bp
Antitoxin
Download Length: 197 a.a. Molecular weight: 23313.88 Da Isoelectric Point: 7.8482
>AT292383 WP_014621283.1 NZ_LS483339:c162819-162229 [Streptococcus thermophilus]
MSKKEILFEFIENHNGIITYKDCKALKIPTIYLTRLEKEGILYRVEKGIFLTQNGDYDEYYFFQYRYPKAIFSYISALYL
QQFTDEIPQYFDVTIPRGYRFNTPPANLNIHSVSKEYSELGITLVKTPMGNEVRVYDLERIICDFVIHREKIDTELFVKT
LQHYGNYSKKNLTKLYEYATKMNTLDKVKQTLEVLV
MSKKEILFEFIENHNGIITYKDCKALKIPTIYLTRLEKEGILYRVEKGIFLTQNGDYDEYYFFQYRYPKAIFSYISALYL
QQFTDEIPQYFDVTIPRGYRFNTPPANLNIHSVSKEYSELGITLVKTPMGNEVRVYDLERIICDFVIHREKIDTELFVKT
LQHYGNYSKKNLTKLYEYATKMNTLDKVKQTLEVLV
Download Length: 591 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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