Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 840571..841048 Replicon chromosome
Accession NZ_LS483316
Organism Staphylococcus aureus strain NCTC13395

Toxin (Protein)


Gene name TsaT Uniprot ID Q2G005
Locus tag DQL73_RS04210 Protein ID WP_000052078.1
Coordinates 840571..840759 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID T1Y6P8
Locus tag DQL73_RS04215 Protein ID WP_001059690.1
Coordinates 840788..841048 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL73_RS04180 836612..837082 + 471 WP_000824472.1 hypothetical protein -
DQL73_RS04185 837423..838109 + 687 WP_001548082.1 thermonuclease family protein -
DQL73_RS04190 838466..838666 + 201 WP_001059082.1 cold-shock protein -
DQL73_RS04195 839162..839380 - 219 WP_000005886.1 hypothetical protein -
DQL73_RS04200 839442..839726 - 285 WP_001004395.1 hypothetical protein -
DQL73_RS04205 839814..840383 - 570 WP_001106654.1 hypothetical protein -
DQL73_RS04210 840571..840759 - 189 WP_000052078.1 hypothetical protein Toxin
DQL73_RS04215 840788..841048 - 261 WP_001059690.1 hypothetical protein Antitoxin
DQL73_RS04220 841389..841592 + 204 WP_000145163.1 sterile alpha motif-like domain-containing protein -
DQL73_RS04225 841589..841825 - 237 WP_000368687.1 hypothetical protein -
DQL73_RS04230 842050..842631 + 582 WP_001140686.1 phosphoglycerate mutase family protein -
DQL73_RS04235 842704..843321 - 618 WP_000255561.1 LysE/ArgO family amino acid transporter -
DQL73_RS04240 843476..843970 - 495 WP_000569884.1 GNAT family N-acetyltransferase -
DQL73_RS04245 844369..844791 - 423 WP_000974460.1 organic hydroperoxide resistance protein -
DQL73_RS04250 844939..845655 + 717 WP_000150017.1 type I 3-dehydroquinate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7172.84 Da        Isoelectric Point: 9.9971

>T292316 WP_000052078.1 NZ_LS483316:c840759-840571 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTSKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Download         Length: 189 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9940.09 Da        Isoelectric Point: 4.0624

>AT292316 WP_001059690.1 NZ_LS483316:c841048-840788 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0D6HZ40

Antitoxin

Source ID Structure
AlphaFold DB A0A0E0VN56

References