292309

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TscAT/-
Location 2048061..2048572 Replicon chromosome
Accession NZ_LS483314
Organism Staphylococcus aureus strain NCTC3761

Toxin (Protein)


Gene name TscT Uniprot ID -
Locus tag DQL90_RS10550 Protein ID WP_001103943.1
Coordinates 2048061..2048360 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name TscA Uniprot ID -
Locus tag DQL90_RS10555 Protein ID WP_001058486.1
Coordinates 2048363..2048572 (-) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL90_RS10520 2043211..2043789 - 579 WP_000846292.1 hypothetical protein -
DQL90_RS10525 2043801..2044142 - 342 WP_001161659.1 hypothetical protein -
DQL90_RS10530 2044489..2045130 - 642 WP_001019765.1 hypothetical protein -
DQL90_RS10535 2045132..2045404 - 273 WP_001149387.1 hypothetical protein -
DQL90_RS10540 2045391..2046194 - 804 WP_000148374.1 bifunctional DNA primase/polymerase -
DQL90_RS10545 2046370..2047986 - 1617 WP_111688665.1 phage resistance protein -
DQL90_RS10550 2048061..2048360 - 300 WP_001103943.1 DUF1474 family protein Toxin
DQL90_RS10555 2048363..2048572 - 210 WP_001058486.1 hypothetical protein Antitoxin
DQL90_RS10560 2048565..2048711 - 147 WP_000784875.1 hypothetical protein -
DQL90_RS10565 2048708..2049025 - 318 WP_000459698.1 helix-turn-helix domain-containing protein -
DQL90_RS10570 2049029..2049241 - 213 WP_000794315.1 helix-turn-helix transcriptional regulator -
DQL90_RS10575 2049415..2050047 + 633 WP_000616253.1 helix-turn-helix transcriptional regulator -
DQL90_RS10580 2050056..2051228 + 1173 WP_000179352.1 site-specific integrase -
DQL90_RS10585 2051297..2052913 - 1617 WP_000240645.1 chaperonin GroEL -
DQL90_RS10590 2052989..2053273 - 285 WP_000917289.1 co-chaperone GroES -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - groEL 2028057..2053273 25216


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF1474

(1-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11795.24 Da        Isoelectric Point: 4.5689

>T292309 WP_001103943.1 NZ_LS483314:c2048360-2048061 [Staphylococcus aureus]
MNWEIKDLMCDIEVIKQKINDVATKHAWFVEDRFVKNELETKREHINFSASYLEHRIQNEHTVELLQVYLKEFDELIQKF
HEIEKASSDVSLATESDDA

Download         Length: 300 bp

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 8252.31 Da        Isoelectric Point: 4.3718

>AT292309 WP_001058486.1 NZ_LS483314:c2048572-2048363 [Staphylococcus aureus]
MNNEQKEVIEHLVYQLELSVMNNLESYEHTEYVNGIEVVSEISREKHLELIMKWCAQELKNNFQLEKGE

Download         Length: 210 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References