Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 839232..839709 Replicon chromosome
Accession NZ_LS483314
Organism Staphylococcus aureus strain NCTC3761

Toxin (Protein)


Gene name TsaT Uniprot ID T1Y7S2
Locus tag DQL90_RS04200 Protein ID WP_000052076.1
Coordinates 839232..839420 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID T1Y6P8
Locus tag DQL90_RS04205 Protein ID WP_001059690.1
Coordinates 839449..839709 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL90_RS04170 835274..835744 + 471 WP_000824472.1 hypothetical protein -
DQL90_RS04175 836085..836771 + 687 WP_001548082.1 thermonuclease family protein -
DQL90_RS04180 837128..837328 + 201 WP_001059082.1 cold-shock protein -
DQL90_RS04185 837823..838041 - 219 WP_000005884.1 hypothetical protein -
DQL90_RS04190 838103..838387 - 285 WP_001004394.1 hypothetical protein -
DQL90_RS04195 838475..839044 - 570 WP_001106653.1 hypothetical protein -
DQL90_RS04200 839232..839420 - 189 WP_000052076.1 hypothetical protein Toxin
DQL90_RS04205 839449..839709 - 261 WP_001059690.1 hypothetical protein Antitoxin
DQL90_RS04210 840050..840253 + 204 WP_000145163.1 sterile alpha motif-like domain-containing protein -
DQL90_RS04215 840250..840486 - 237 WP_000368687.1 hypothetical protein -
DQL90_RS04220 840711..841292 + 582 WP_172449172.1 phosphoglycerate mutase family protein -
DQL90_RS04225 841365..841982 - 618 WP_000255553.1 LysE/ArgO family amino acid transporter -
DQL90_RS04230 842137..842631 - 495 WP_000569884.1 GNAT family N-acetyltransferase -
DQL90_RS04235 843030..843452 - 423 WP_000974460.1 organic hydroperoxide resistance protein -
DQL90_RS04240 843600..844316 + 717 WP_000150013.1 type I 3-dehydroquinate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7142.82 Da        Isoelectric Point: 9.9971

>T292307 WP_000052076.1 NZ_LS483314:c839420-839232 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Download         Length: 189 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9940.09 Da        Isoelectric Point: 4.0624

>AT292307 WP_001059690.1 NZ_LS483314:c839709-839449 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0VP18

Antitoxin

Source ID Structure
AlphaFold DB A0A0E0VN56

References