Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | tsbAT/- |
Location | 1831106..1831882 | Replicon | chromosome |
Accession | NZ_LS483310 | ||
Organism | Staphylococcus aureus strain NCTC9752 |
Toxin (Protein)
Gene name | tsbT | Uniprot ID | X5E2E6 |
Locus tag | DQL84_RS09240 | Protein ID | WP_000031108.1 |
Coordinates | 1831106..1831258 (-) | Length | 51 a.a. |
Antitoxin (Protein)
Gene name | tsbA | Uniprot ID | W8U4V4 |
Locus tag | DQL84_RS09245 | Protein ID | WP_001251224.1 |
Coordinates | 1831283..1831882 (-) | Length | 200 a.a. |
Genomic Context
Location: 1827313..1828134 (822 bp)
Type: Others
Protein ID: WP_000669376.1
Type: Others
Protein ID: WP_000669376.1
Location: 1828586..1829971 (1386 bp)
Type: Others
Protein ID: WP_000116229.1
Type: Others
Protein ID: WP_000116229.1
Location: 1830167..1830562 (396 bp)
Type: Others
Protein ID: WP_000901023.1
Type: Others
Protein ID: WP_000901023.1
Location: 1831106..1831258 (153 bp)
Type: Toxin
Protein ID: WP_000031108.1
Type: Toxin
Protein ID: WP_000031108.1
Location: 1831283..1831882 (600 bp)
Type: Antitoxin
Protein ID: WP_001251224.1
Type: Antitoxin
Protein ID: WP_001251224.1
Location: 1832041..1832511 (471 bp)
Type: Others
Protein ID: WP_000181394.1
Type: Others
Protein ID: WP_000181394.1
Location: 1832516..1833643 (1128 bp)
Type: Others
Protein ID: WP_000379980.1
Type: Others
Protein ID: WP_000379980.1
Location: 1833795..1834517 (723 bp)
Type: Others
Protein ID: WP_000590809.1
Type: Others
Protein ID: WP_000590809.1
Location: 1834510..1835967 (1458 bp)
Type: Others
Protein ID: WP_000649907.1
Type: Others
Protein ID: WP_000649907.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
DQL84_RS09220 | 1827313..1828134 | + | 822 | WP_000669376.1 | RluA family pseudouridine synthase | - |
DQL84_RS09225 | 1828586..1829971 | - | 1386 | WP_000116229.1 | class II fumarate hydratase | - |
DQL84_RS09230 | 1830167..1830562 | - | 396 | WP_000901023.1 | hypothetical protein | - |
DQL84_RS09240 | 1831106..1831258 | - | 153 | WP_000031108.1 | hypothetical protein | Toxin |
DQL84_RS09245 | 1831283..1831882 | - | 600 | WP_001251224.1 | glucosamine-6-phosphate isomerase | Antitoxin |
DQL84_RS09250 | 1832041..1832511 | - | 471 | WP_000181394.1 | tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL | - |
DQL84_RS09255 | 1832516..1833643 | - | 1128 | WP_000379980.1 | tRNA epoxyqueuosine(34) reductase QueG | - |
DQL84_RS09260 | 1833795..1834517 | - | 723 | WP_000590809.1 | amino acid ABC transporter ATP-binding protein | - |
DQL84_RS09265 | 1834510..1835967 | - | 1458 | WP_000649907.1 | ABC transporter permease subunit | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 51 a.a. Molecular weight: 5936.28 Da Isoelectric Point: 3.8962
>T292276 WP_000031108.1 NZ_LS483310:c1831258-1831106 [Staphylococcus aureus]
MSKDKDPKLNYHEEENSMVTDFEDLKELGKEMEQISDQNDQEKNSEEDSQ
MSKDKDPKLNYHEEENSMVTDFEDLKELGKEMEQISDQNDQEKNSEEDSQ
Download Length: 153 bp
Antitoxin
Download Length: 200 a.a. Molecular weight: 22343.47 Da Isoelectric Point: 5.1445
>AT292276 WP_001251224.1 NZ_LS483310:c1831882-1831283 [Staphylococcus aureus]
MAMNFKVFDNSQLVAEYAADIIRKQFNNNPTTIAGFHLDTDQAPVLDELKKNVEKHAVDFSQINILDYDDKKSYFEALGV
PAGQVYPIAYEKDAIELIADKIKTKENKGKLTLQVVSIDEQGKLNVSIRQGLMEAREIFLVVTGANKRDVVEKLYQENGK
TSFEPADLKAHRMVNVILDKEAAAGLPEDVKAYFTSRFA
MAMNFKVFDNSQLVAEYAADIIRKQFNNNPTTIAGFHLDTDQAPVLDELKKNVEKHAVDFSQINILDYDDKKSYFEALGV
PAGQVYPIAYEKDAIELIADKIKTKENKGKLTLQVVSIDEQGKLNVSIRQGLMEAREIFLVVTGANKRDVVEKLYQENGK
TSFEPADLKAHRMVNVILDKEAAAGLPEDVKAYFTSRFA
Download Length: 600 bp