Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 1052414..1053164 Replicon chromosome
Accession NZ_LS483305
Organism Mammaliicoccus sciuri strain NCTC12103

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag DQL71_RS05140 Protein ID WP_101494413.1
Coordinates 1053057..1053164 (+) Length 36 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag DQL71_RS05135 Protein ID WP_048539838.1
Coordinates 1052414..1053013 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL71_RS05115 1047777..1048538 + 762 WP_048539835.1 acetylglutamate kinase -
DQL71_RS05120 1049348..1050475 + 1128 WP_048539836.1 tRNA epoxyqueuosine(34) reductase QueG -
DQL71_RS05125 1050479..1050952 + 474 WP_025904798.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
DQL71_RS13945 1050987..1051127 - 141 WP_162841915.1 hypothetical protein -
DQL71_RS05130 1051214..1052365 + 1152 WP_048539837.1 N-acetylglucosamine-6-phosphate deacetylase -
DQL71_RS05135 1052414..1053013 + 600 WP_048539838.1 glucosamine-6-phosphate isomerase Antitoxin
DQL71_RS05140 1053057..1053164 + 108 WP_101494413.1 hypothetical protein Toxin
DQL71_RS05145 1053317..1054705 + 1389 WP_048539839.1 class II fumarate hydratase -
DQL71_RS05150 1054795..1056321 + 1527 WP_048539840.1 exopolyphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(134-195)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4130.43 Da        Isoelectric Point: 3.7615

>T292242 WP_101494413.1 NZ_LS483305:1053057-1053164 [Mammaliicoccus sciuri]
MVQDLEDVKELGKEMEQISEQNDEAFEEKKSEQES

Download         Length: 108 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22290.17 Da        Isoelectric Point: 4.9758

>AT292242 WP_048539838.1 NZ_LS483305:1052414-1053013 [Mammaliicoccus sciuri]
MALNFKVFETKDIAARYAADVVRKQFNSDSTSVVGVHLEAEQTSFFDELLDDVKKNPVNFSQIHILDFDGKEDYYTELGV
PAKQVLKTDVGSDVEAFIKEKVNTDKKKNKLMLDVVTLTEDSRTGLDYNQAIHPAREVIVLVTGKEKAKAVSQLYQEPAN
GSVESAKLKQHRMVTVVLDNEAAQGLPEDVRSYFSIQFS

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References