Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 978448..979221 Replicon chromosome
Accession NZ_LS483304
Organism Staphylococcus hyicus strain NCTC10350

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag DQL55_RS11945 Protein ID WP_167693803.1
Coordinates 979066..979221 (+) Length 52 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID A0A0A8HNH4
Locus tag DQL55_RS04605 Protein ID WP_039644857.1
Coordinates 978448..979047 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL55_RS04585 974757..975479 + 723 WP_039644852.1 amino acid ABC transporter ATP-binding protein -
DQL55_RS04590 975645..976772 + 1128 WP_039644853.1 tRNA epoxyqueuosine(34) reductase QueG -
DQL55_RS04595 976775..977245 + 471 WP_039644854.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
DQL55_RS04600 977261..978430 + 1170 WP_039644856.1 N-acetylglucosamine-6-phosphate deacetylase -
DQL55_RS04605 978448..979047 + 600 WP_039644857.1 glucosamine-6-phosphate isomerase Antitoxin
DQL55_RS11945 979066..979221 + 156 WP_167693803.1 hypothetical protein Toxin
DQL55_RS04610 979377..979781 + 405 WP_039644859.1 hypothetical protein -
DQL55_RS04615 979939..981324 + 1386 WP_039644862.1 class II fumarate hydratase -
DQL55_RS04620 981346..982872 + 1527 WP_039644866.1 exopolyphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 52 a.a.        Molecular weight: 5989.31 Da        Isoelectric Point: 3.9940

>T292239 WP_167693803.1 NZ_LS483304:979066-979221 [Staphylococcus hyicus]
MSEEKHIEHENEMVDNFDDLVQLGKEMEQISETNDQDKLNQSHDSEGRSNQ

Download         Length: 156 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22363.41 Da        Isoelectric Point: 6.0248

>AT292239 WP_039644857.1 NZ_LS483304:978448-979047 [Staphylococcus hyicus]
MAMNFKVFKDKDTAAIYAADIIRKQFNNNPTTIAGFHLNEEAAPVLDYLKRNVDDHAVDFSQIHILDYDKQTSYFKALGV
PEKQIHEIPEEDEVEKFIERKAKTKDNKGKLTLQVVSINNKGEFGIPVTNGLKPAREIFVVVTGSEKADVIKKLYEDNGN
TSFIPSSLKAHRMVNVILDEAAAQGLPDDVRAYFTSLYA

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0A8HNH4

References