Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 877735..878212 Replicon chromosome
Accession NZ_LS483301
Organism Staphylococcus aureus strain NCTC13394

Toxin (Protein)


Gene name TsaT Uniprot ID Q2G005
Locus tag DQL88_RS04480 Protein ID WP_000052078.1
Coordinates 877735..877923 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID T1Y6P8
Locus tag DQL88_RS04485 Protein ID WP_001059690.1
Coordinates 877952..878212 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL88_RS04450 873777..874247 + 471 WP_000824472.1 hypothetical protein -
DQL88_RS04455 874588..875274 + 687 WP_001548082.1 thermonuclease family protein -
DQL88_RS04460 875631..875831 + 201 WP_001059082.1 cold-shock protein -
DQL88_RS04465 876327..876544 - 218 Protein_825 hypothetical protein -
DQL88_RS04470 876606..876890 - 285 WP_001004395.1 hypothetical protein -
DQL88_RS04475 876978..877547 - 570 WP_001106654.1 hypothetical protein -
DQL88_RS04480 877735..877923 - 189 WP_000052078.1 hypothetical protein Toxin
DQL88_RS04485 877952..878212 - 261 WP_001059690.1 hypothetical protein Antitoxin
DQL88_RS04490 878553..878756 + 204 WP_000145163.1 sterile alpha motif-like domain-containing protein -
DQL88_RS04495 878753..878989 - 237 WP_000368687.1 hypothetical protein -
DQL88_RS04500 879214..879795 + 582 WP_001140686.1 phosphoglycerate mutase family protein -
DQL88_RS04505 879868..880485 - 618 WP_000255561.1 LysE/ArgO family amino acid transporter -
DQL88_RS04510 880640..881134 - 495 WP_000569884.1 GNAT family N-acetyltransferase -
DQL88_RS04515 881533..881955 - 423 WP_000974460.1 organic hydroperoxide resistance protein -
DQL88_RS04520 882103..882819 + 717 WP_000150017.1 type I 3-dehydroquinate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7172.84 Da        Isoelectric Point: 9.9971

>T292199 WP_000052078.1 NZ_LS483301:c877923-877735 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTSKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Download         Length: 189 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9940.09 Da        Isoelectric Point: 4.0624

>AT292199 WP_001059690.1 NZ_LS483301:c878212-877952 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0D6HZ40

Antitoxin

Source ID Structure
AlphaFold DB A0A0E0VN56

References