292189

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 831740..832217 Replicon chromosome
Accession NZ_LS483300
Organism Staphylococcus aureus strain NCTC7485

Toxin (Protein)


Gene name TsaT Uniprot ID T1Y7S2
Locus tag DQL62_RS04210 Protein ID WP_000052076.1
Coordinates 831740..831928 (-) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID -
Locus tag DQL62_RS04215 Protein ID WP_001059749.1
Coordinates 831957..832217 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQL62_RS04180 827743..828252 + 510 WP_045158736.1 hypothetical protein -
DQL62_RS04185 828593..829279 + 687 WP_011382230.1 thermonuclease family protein -
DQL62_RS04190 829636..829836 + 201 WP_001059082.1 cold-shock protein -
DQL62_RS04195 830331..830549 - 219 WP_000005883.1 hypothetical protein -
DQL62_RS04200 830611..830895 - 285 WP_001004397.1 hypothetical protein -
DQL62_RS04205 830983..831552 - 570 WP_001106648.1 hypothetical protein -
DQL62_RS04210 831740..831928 - 189 WP_000052076.1 hypothetical protein Toxin
DQL62_RS04215 831957..832217 - 261 WP_001059749.1 hypothetical protein Antitoxin
DQL62_RS04220 832558..832761 + 204 WP_000145163.1 sterile alpha motif-like domain-containing protein -
DQL62_RS04225 832758..832994 - 237 WP_000368687.1 hypothetical protein -
DQL62_RS04230 833219..833800 + 582 WP_001140696.1 phosphoglycerate mutase family protein -
DQL62_RS04235 833873..834490 - 618 WP_000255553.1 LysE/ArgO family amino acid transporter -
DQL62_RS04240 834646..835140 - 495 WP_000569881.1 GNAT family N-acetyltransferase -
DQL62_RS04245 835539..835961 - 423 WP_000974458.1 organic hydroperoxide resistance protein -
DQL62_RS04250 836109..836825 + 717 WP_000150029.1 type I 3-dehydroquinate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7142.82 Da        Isoelectric Point: 9.9971

>T292189 WP_000052076.1 NZ_LS483300:c831928-831740 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Download         Length: 189 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9914.01 Da        Isoelectric Point: 4.0624

>AT292189 WP_001059749.1 NZ_LS483300:c832217-831957 [Staphylococcus aureus]
MNNILSNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0VP18

Antitoxin

Source ID Structure

References