Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2020327..2020598 Replicon chromosome
Accession NZ_LS483297
Organism Escherichia coli strain NCTC11023

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2020457..2020560 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2020327..2020598 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DQM98_RS10365 2016882..2017544 - 663 WP_000944256.1 exodeoxyribonuclease X -
DQM98_RS10370 2017568..2018224 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein -
DQM98_RS10375 2018326..2018556 - 231 WP_000916763.1 DNA polymerase III subunit theta -
DQM98_RS10380 2018695..2019069 + 375 WP_000168747.1 CopC domain-containing protein YobA -
DQM98_RS10385 2019073..2019945 + 873 WP_109866052.1 copper homeostasis membrane protein CopD -
DQM98_RS10390 2019958..2020299 + 342 WP_000976476.1 YebY family protein -
- 2020327..2020598 - 272 - - Antitoxin
- 2020457..2020560 + 104 - - Toxin
DQM98_RS10395 2020695..2021351 + 657 WP_000812720.1 protein-serine/threonine phosphatase -
DQM98_RS10400 2021352..2021543 - 192 WP_001296140.1 YebW family protein -
DQM98_RS10405 2021648..2021884 - 237 WP_001295499.1 DUF1480 family protein -
DQM98_RS10410 2022002..2023441 - 1440 WP_024176540.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T292177 NZ_LS483297:2020457-2020560 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT292177 NZ_LS483297:c2020598-2020327 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References