Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 3948923..3949437 Replicon chromosome
Accession NZ_LS483250
Organism Moritella yayanosii strain DB21MT 5

Toxin (Protein)


Gene name relE Uniprot ID A6FHK9
Locus tag MORIYA_RS18370 Protein ID WP_006033866.1
Coordinates 3948923..3949186 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag MORIYA_RS18375 Protein ID WP_112717551.1
Coordinates 3949186..3949437 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MORIYA_RS18350 3944871..3945815 + 945 WP_112717543.1 DNA-binding transcriptional regulator DsdC -
MORIYA_RS18355 3945812..3947101 - 1290 WP_112717545.1 alpha/beta fold hydrolase -
MORIYA_RS18360 3947239..3947850 - 612 WP_112717547.1 LysE family translocator -
MORIYA_RS18365 3947959..3948885 + 927 WP_112717549.1 LysR family transcriptional regulator -
MORIYA_RS18370 3948923..3949186 - 264 WP_006033866.1 Txe/YoeB family addiction module toxin Toxin
MORIYA_RS18375 3949186..3949437 - 252 WP_112717551.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
MORIYA_RS18380 3949532..3950290 - 759 WP_112717553.1 endonuclease -
MORIYA_RS18385 3950544..3950774 - 231 WP_112717555.1 hypothetical protein -
MORIYA_RS18390 3950924..3951442 - 519 WP_112717557.1 SprT family zinc-dependent metalloprotease -
MORIYA_RS18395 3951579..3952730 - 1152 WP_112717559.1 methionine adenosyltransferase -
MORIYA_RS18400 3953310..3953846 + 537 WP_112717561.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10467.97 Da        Isoelectric Point: 9.9593

>T292136 WP_006033866.1 NZ_LS483250:c3949186-3948923 [Moritella yayanosii]
MRNILFTPHAWEDYTYWQTQDKRTLKRINKLIEAVQRMPFEGIGKPEPLKENLTGYWSRRINDEHRLVYKAGDDVVTIVS
TRFHYGK

Download         Length: 264 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9322.46 Da        Isoelectric Point: 4.6081

>AT292136 WP_112717551.1 NZ_LS483250:c3949437-3949186 [Moritella yayanosii]
MSVVTFSEARNNFKSICDSAVDDCEPVHIHRRGGEDVVLLSASEFNAWKETMYLMANPNNSKRLLESIAQAEHGEVLNKE
LLD

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A6FHK9

Antitoxin

Source ID Structure

References