Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3990137..3990803 Replicon chromosome
Accession NZ_LR994655
Organism Serratia sp. Tan611 isolate Serratia sp. Tan611

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag TAN611_RS18820 Protein ID WP_105232394.1
Coordinates 3990137..3990556 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag TAN611_RS18825 Protein ID WP_105232395.1
Coordinates 3990537..3990803 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TAN611_RS18800 3986110..3987840 - 1731 WP_105232391.1 single-stranded-DNA-specific exonuclease RecJ -
TAN611_RS18805 3987853..3988569 - 717 WP_015673664.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
TAN611_RS18810 3988597..3989496 - 900 WP_105232392.1 site-specific tyrosine recombinase XerD -
TAN611_RS18815 3989588..3990106 + 519 WP_105232393.1 flavodoxin FldB -
TAN611_RS18820 3990137..3990556 - 420 WP_105232394.1 hypothetical protein Toxin
TAN611_RS18825 3990537..3990803 - 267 WP_105232395.1 FAD assembly factor SdhE Antitoxin
TAN611_RS18830 3991134..3992126 + 993 WP_105232396.1 tRNA-modifying protein YgfZ -
TAN611_RS18835 3992163..3992843 - 681 WP_105232397.1 hemolysin III family protein -
TAN611_RS18840 3993038..3993646 + 609 WP_105232398.1 HD domain-containing protein -
TAN611_RS18845 3993680..3994999 - 1320 WP_105232399.1 MHS family MFS transporter -
TAN611_RS18850 3994996..3995649 - 654 WP_203066869.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16481.54 Da        Isoelectric Point: 11.5037

>T292105 WP_105232394.1 NZ_LR994655:c3990556-3990137 [Serratia sp. Tan611]
VAQWRCDVRISWRTQLISLLAHGALILLILISPWPESYDPVWLLLLTLVVFECIRSQTRIASRQGELRLLSAPQRVIWQG
KEWRLVRRPWMLRYGMLLTLQASGKRKRRRLWLASDCISSAEWRQLCQRMRLVKDESEG

Download         Length: 420 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10405.90 Da        Isoelectric Point: 5.0964

>AT292105 WP_105232395.1 NZ_LR994655:c3990803-3990537 [Serratia sp. Tan611]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSEEDKALFVRLLQCDDPDLFNWLMNHGAPQDAELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References