Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 1000693..1001463 Replicon chromosome
Accession NZ_LR962863
Organism Staphylococcus schleiferi strain NCTC12218

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag JM183_RS04680 Protein ID WP_016425469.1
Coordinates 1001311..1001463 (+) Length 51 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag JM183_RS04675 Protein ID WP_126496416.1
Coordinates 1000693..1001292 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JM183_RS04655 (NCTC12218_00986) 996682..998142 + 1461 WP_126496414.1 ABC transporter permease subunit -
JM183_RS04660 (NCTC12218_00987) 998135..998863 + 729 WP_126496415.1 amino acid ABC transporter ATP-binding protein -
JM183_RS04665 999039..1000043 + 1005 Protein_893 tRNA epoxyqueuosine(34) reductase QueG -
JM183_RS04670 (NCTC12218_00991) 1000043..1000513 + 471 WP_016425471.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
JM183_RS04675 (NCTC12218_00992) 1000693..1001292 + 600 WP_126496416.1 glucosamine-6-phosphate isomerase Antitoxin
JM183_RS04680 (NCTC12218_00993) 1001311..1001463 + 153 WP_016425469.1 SAS053 family protein Toxin
JM183_RS04685 (NCTC12218_00994) 1001613..1002038 + 426 WP_016425468.1 hypothetical protein -
JM183_RS04690 (NCTC12218_00995) 1002210..1003595 + 1386 WP_126496425.1 class II fumarate hydratase -
JM183_RS04695 (NCTC12218_00996) 1003616..1005142 + 1527 WP_016425466.1 exopolyphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(131-197)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5931.35 Da        Isoelectric Point: 3.9615

>T292095 WP_016425469.1 NZ_LR962863:1001311-1001463 [Staphylococcus schleiferi]
MKDDQKQYENEMVEGFDDVVELGKEMEQISEKNDQDKLNQDHDADIRSDK

Download         Length: 153 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22186.11 Da        Isoelectric Point: 5.5527

>AT292095 WP_126496416.1 NZ_LR962863:1000693-1001292 [Staphylococcus schleiferi]
MAMNFKIFKDAETVAKYTADILRKQLNNNPTSIVGVHLNEDQATVLNFLKQDVDRHSVDFSQIHILDYDKQASFFKSLGV
PEKQVHEVPDDDNVESFIAHHAKTKDNKGKLTLQVLTIDENGQIGLPMNDAVMPAREIIVVVTGSNKAAQVQKLYEENGN
TSFIPSTLKTHRMVTVVLDEAAAQGLPDDVRAYFTSLYA

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References