Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2961858..2962092 | Replicon | chromosome |
| Accession | NZ_LR898874 | ||
| Organism | Escherichia coli isolate MSB1_4I-sc-2280412 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2961859..2961962 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2961858..2962092 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JMX41_RS14625 | 2959056..2959865 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| JMX41_RS14630 | 2959922..2960116 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| JMX41_RS14635 | 2960109..2960297 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 2960115..2960293 | - | 179 | NuclAT_1 | - | - |
| - | 2960115..2960293 | - | 179 | NuclAT_1 | - | - |
| - | 2960115..2960293 | - | 179 | NuclAT_1 | - | - |
| - | 2960115..2960293 | - | 179 | NuclAT_1 | - | - |
| JMX41_RS14640 | 2960404..2960685 | + | 282 | WP_001311878.1 | excisionase | - |
| JMX41_RS14645 | 2960651..2961727 | + | 1077 | WP_016236038.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2961858..2962092 | + | 235 | - | - | Antitoxin |
| - | 2961859..2961962 | - | 104 | - | - | Toxin |
| JMX41_RS14650 | 2962120..2962461 | - | 342 | WP_000976472.1 | YebY family protein | - |
| JMX41_RS14655 | 2962474..2963346 | - | 873 | WP_000879331.1 | copper homeostasis membrane protein CopD | - |
| JMX41_RS14660 | 2963350..2963724 | - | 375 | WP_000168737.1 | CopC domain-containing protein YobA | - |
| JMX41_RS14665 | 2963863..2964093 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| JMX41_RS14670 | 2964195..2964851 | + | 657 | WP_001571542.1 | carbon-nitrogen hydrolase family protein | - |
| JMX41_RS14675 | 2964875..2965537 | + | 663 | WP_000944240.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2906858..2967585 | 60727 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T292070 NZ_LR898874:c2961962-2961859 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT292070 NZ_LR898874:2961858-2962092 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
