Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1860210..1860355 Replicon chromosome
Accession NZ_LR890735
Organism Klebsiella pneumoniae isolate INF323-sc-2280125

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1860246..1860348 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1860210..1860355 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMX74_RS09130 1855340..1857400 + 2061 WP_201720497.1 oligopeptidase B -
JMX74_RS09135 1857404..1858063 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMX74_RS09140 1858142..1858372 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMX74_RS09145 1858485..1858859 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMX74_RS09150 1858863..1859732 + 870 WP_023280292.1 copper homeostasis membrane protein CopD -
JMX74_RS09155 1859749..1860087 + 339 WP_002911404.1 YebY family protein -
- 1860210..1860355 - 146 - - Antitoxin
- 1860246..1860348 + 103 - - Toxin
JMX74_RS09160 1860724..1860867 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMX74_RS09165 1860972..1861940 - 969 WP_004151446.1 VirK/YbjX family protein -
JMX74_RS09170 1862097..1862750 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
JMX74_RS09175 1862747..1862938 - 192 WP_002911395.1 YebW family protein -
JMX74_RS09180 1863036..1863275 - 240 WP_002911393.1 YebV family protein -
JMX74_RS09185 1863391..1864824 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291995 NZ_LR890735:1860246-1860348 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291995 NZ_LR890735:c1860355-1860210 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References