Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1886187..1886332 Replicon chromosome
Accession NZ_LR890722
Organism Klebsiella pneumoniae isolate KSB1_1H

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1886223..1886325 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1886187..1886332 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW72_RS09120 1881317..1883377 + 2061 WP_004151449.1 oligopeptidase B -
JMW72_RS09125 1883381..1884040 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMW72_RS09130 1884119..1884349 - 231 WP_040147502.1 DNA polymerase III subunit theta -
JMW72_RS09135 1884462..1884836 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMW72_RS09140 1884840..1885709 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
JMW72_RS09145 1885726..1886064 + 339 WP_002911404.1 YebY family protein -
- 1886187..1886332 - 146 - - Antitoxin
- 1886223..1886325 + 103 - - Toxin
JMW72_RS09150 1886700..1886843 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMW72_RS09155 1886948..1887916 - 969 WP_004151446.1 VirK/YbjX family protein -
JMW72_RS09160 1888073..1888726 + 654 WP_032415192.1 protein-serine/threonine phosphatase -
JMW72_RS09165 1888723..1888914 - 192 WP_002911395.1 YebW family protein -
JMW72_RS09170 1889012..1889251 - 240 WP_002911393.1 YebV family protein -
JMW72_RS09175 1889367..1890800 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291965 NZ_LR890722:1886223-1886325 [Klebsiella pneumoniae]
GCAAGGCGGCTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291965 NZ_LR890722:c1886332-1886187 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGCCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References