Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1888470..1888615 Replicon chromosome
Accession NZ_LR890710
Organism Klebsiella pneumoniae isolate KSB2_9B

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1888506..1888608 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1888470..1888615 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMX55_RS09190 1883600..1885660 + 2061 WP_004151449.1 oligopeptidase B -
JMX55_RS09195 1885664..1886323 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMX55_RS09200 1886402..1886632 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMX55_RS09205 1886745..1887119 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMX55_RS09210 1887123..1887992 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
JMX55_RS09215 1888009..1888347 + 339 WP_016529031.1 YebY family protein -
- 1888470..1888615 - 146 - - Antitoxin
- 1888506..1888608 + 103 - - Toxin
JMX55_RS09220 1888984..1889127 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMX55_RS09225 1889232..1890200 - 969 WP_074185275.1 DUF535 family protein -
JMX55_RS09230 1890357..1891010 + 654 WP_032447686.1 protein-serine/threonine phosphatase -
JMX55_RS09235 1891007..1891198 - 192 WP_002911395.1 YebW family protein -
JMX55_RS09240 1891296..1891535 - 240 WP_002911393.1 YebV family protein -
JMX55_RS09245 1891651..1893084 - 1434 WP_032447684.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291909 NZ_LR890710:1888506-1888608 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291909 NZ_LR890710:c1888615-1888470 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References