Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1537918..1538063 Replicon chromosome
Accession NZ_LR890702
Organism Klebsiella pneumoniae isolate INF305-sc-2280094

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1537925..1538027 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1537918..1538063 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMX64_RS07705 1533449..1534882 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
JMX64_RS07710 1534998..1535237 + 240 WP_002911393.1 YebV family protein -
JMX64_RS07715 1535335..1535526 + 192 WP_002911395.1 YebW family protein -
JMX64_RS07720 1535523..1536176 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
JMX64_RS07725 1536333..1537301 + 969 WP_004151446.1 VirK/YbjX family protein -
JMX64_RS07730 1537406..1537549 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1537918..1538063 + 146 - - Antitoxin
- 1537925..1538027 - 103 - - Toxin
JMX64_RS07735 1538186..1538524 - 339 WP_002911404.1 YebY family protein -
JMX64_RS07740 1538541..1539410 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
JMX64_RS07745 1539414..1539788 - 375 WP_004151448.1 CopC domain-containing protein YobA -
JMX64_RS07750 1539901..1540131 + 231 WP_002911406.1 DNA polymerase III subunit theta -
JMX64_RS07755 1540210..1540869 + 660 WP_002911407.1 exodeoxyribonuclease X -
JMX64_RS07760 1540873..1542933 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291887 NZ_LR890702:c1538027-1537925 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291887 NZ_LR890702:1537918-1538063 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References