291870

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX-GNAT
Location 3996928..3997748 Replicon chromosome
Accession NZ_LR890693
Organism Escherichia coli isolate MSB1_4E-sc-2280348

Toxin (Protein)


Gene name yjhX Uniprot ID B6I030
Locus tag JMW23_RS19475 Protein ID WP_001054379.1
Coordinates 3997491..3997748 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag JMW23_RS19470 Protein ID WP_000123957.1
Coordinates 3996928..3997479 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW23_RS19440 3992622..3993935 - 1314 WP_000460845.1 galactitol-specific PTS transporter subunit IIC -
JMW23_RS19445 3993947..3994225 - 279 WP_000722973.1 PTS sugar transporter subunit IIB -
JMW23_RS19450 3994222..3995343 - 1122 WP_000010833.1 M42 family metallopeptidase -
JMW23_RS19455 3995588..3995704 - 117 Protein_3801 VOC family protein -
JMW23_RS19460 3995742..3996002 - 261 WP_000077645.1 hypothetical protein -
JMW23_RS19465 3996130..3996876 - 747 WP_000354249.1 class I SAM-dependent methyltransferase -
JMW23_RS19470 3996928..3997479 - 552 WP_000123957.1 N-acetyltransferase Antitoxin
JMW23_RS19475 3997491..3997748 - 258 WP_001054379.1 YjhX family toxin Toxin
JMW23_RS19480 3998125..3998289 - 165 Protein_3806 GNAT family N-acetyltransferase -
JMW23_RS19490 3999532..4000638 + 1107 Protein_3808 DNA helicase -
JMW23_RS19495 4001221..4002201 - 981 WP_000991462.1 9-O-acetyl-N-acetylneuraminic acid deacetylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(19-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9568.07 Da        Isoelectric Point: 11.1381

>T291870 WP_001054379.1 NZ_LR890693:c3997748-3997491 [Escherichia coli]
MNLSRQEQRTLHVLAKGGRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20358.34 Da        Isoelectric Point: 6.4182

>AT291870 WP_000123957.1 NZ_LR890693:c3997479-3996928 [Escherichia coli]
MTAHHFTFQITDESDASDIREVETRAFGFSKEADLTASLLEDESARPALSLLARHEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQALTA
QPMNVTGHIQCAQALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB B6I030

Antitoxin

Source ID Structure

References