Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 987294..987562 Replicon chromosome
Accession NZ_LR890693
Organism Escherichia coli isolate MSB1_4E-sc-2280348

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 987332..987434 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 987294..987562 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW23_RS05090 984452..985891 + 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
JMW23_RS05095 986008..986244 + 237 WP_001295499.1 DUF1480 family protein -
JMW23_RS05100 986349..986540 + 192 WP_001296140.1 YebW family protein -
JMW23_RS05105 986541..987197 - 657 WP_000812745.1 protein-serine/threonine phosphatase -
- 987294..987562 + 269 - - Antitoxin
- 987332..987434 - 103 - - Toxin
JMW23_RS05110 987592..987933 - 342 WP_000976472.1 YebY family protein -
JMW23_RS05115 987946..988818 - 873 WP_000879317.1 copper homeostasis membrane protein CopD -
JMW23_RS05120 988822..989196 - 375 WP_000168747.1 CopC domain-containing protein YobA -
JMW23_RS05125 989335..989565 + 231 WP_000916763.1 DNA polymerase III subunit theta -
JMW23_RS05130 989667..990323 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
JMW23_RS05135 990347..991009 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291855 NZ_LR890693:c987434-987332 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT291855 NZ_LR890693:987294-987562 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References