Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1882984..1883129 Replicon chromosome
Accession NZ_LR890691
Organism Klebsiella pneumoniae isolate INF119-sc-2279930

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1883020..1883122 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1882984..1883129 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW99_RS09010 1878114..1880174 + 2061 WP_004151449.1 oligopeptidase B -
JMW99_RS09015 1880178..1880837 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMW99_RS09020 1880916..1881146 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMW99_RS09025 1881259..1881633 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMW99_RS09030 1881637..1882506 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
JMW99_RS09035 1882523..1882861 + 339 WP_002911404.1 YebY family protein -
- 1882984..1883129 - 146 - - Antitoxin
- 1883020..1883122 + 103 - - Toxin
JMW99_RS09040 1883497..1883640 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMW99_RS09045 1883745..1884713 - 969 WP_074195444.1 DUF535 family protein -
JMW99_RS09050 1884870..1885523 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
JMW99_RS09055 1885520..1885711 - 192 WP_002911395.1 YebW family protein -
JMW99_RS09060 1885809..1886048 - 240 WP_002911393.1 YebV family protein -
JMW99_RS09065 1886164..1887597 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291836 NZ_LR890691:1883020-1883122 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291836 NZ_LR890691:c1883129-1882984 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References